Results 131 to 140 of about 8,009,603 (305)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
GOVERNANCE QUALITY AND ECONOMIC GROWTH: EVIDENCE FROM SELECTED COUNTRIES IN SUB-SAHARAN AFRICA
Despite copious natural resources and economic potential, some sub-Saharan African countries continue to experience unstable and low economic growth due to weak governance institutions. This study examines the effects of the quality of governance on the
Saheed Akande SHITTU, Lourens J. Erasmus
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Analysing Leadership in Global Health Governance [PDF]
Rhetoric around the need for more and better leadership is everywhere in contemporary global health governance, yet there has been little articulation of what type of leadership is required, who might play leadership roles, and in what fora leadership ...
RUSHTON, S, HARMAN, S
core +1 more source
Accreditation and Patient Safety Culture in Africa: Catalyst for Change or Compliance Burden? [PDF]
Biniam Yohannes Wotango +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Quality of Government and Quality of Water
According to a conservative estimation by the World Health Organization, 1.2 billion people lack access to sufficient quantities of safe water, and 2,6 billion people are without adequate sanitation. Consequently, 80 percent of all illnesses in the developing world are estimated to be the result of waterborne diseases claiming the lives of 1,8 million ...
Holmberg, Sören, Rothstein, Bo
openaire +1 more source
THE QUALITY OF GOVERNANCE IN TRANSITION COUNTRIES
The purpose of this paper is to analyze changes in governance in transition countries and to evaluate their distance to high-income OECD countries. Six variables that consist on governance were analyzed. According to many authors institutions are the most important determinant of long-term economic growth, especially in transition countries ...
openaire +2 more sources
Corporate governance principles and recommendations (3rd ed.) [PDF]
Following a comprehensive review in 2012-13, the 21 members of the ASX Corporate Governance Council (“Council”) agreed that it was an appropriate time to issue a third edition of the Principles and Recommendations.
ASX Corporate Governance Council
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

