Results 51 to 60 of about 738,099 (338)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Does Bank Institutional Setting Affect Board Effectiveness? Evidence from Cooperative and Joint-Stock Banks [PDF]

open access: yes, 2017
Research Question/Issue Do cooperative banks suffer from board deficiencies less frequently and severely than joint-stock banks? To answer this question, we analyze banks operating in Italy during the period 2006–2012 to examine whether the governing ...
Adams   +92 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Twenty Years of Virginia Organizing: A Historical Analysis [PDF]

open access: yes, 2015
Virginia Organizing is a non-profit, non-partisan statewide grassroots community organization aimed at empowering people to affect change in their communities.
Berta, Ruth
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Addressing disruptive medical staff behavior: a 3-year experience [PDF]

open access: yesEinstein (São Paulo)
Objective: To describe the 3-year long experience of addressing disruptive events by medical staff in a private hospital. Methods: The cross-sectional study that was conducted between 2020 and 2022, involved collection, analysis, and management of ...
Fernando Gatti de Menezes   +8 more
doaj   +1 more source

Possible impact of corporate governance profile on a Russian bank valuation [PDF]

open access: yes, 2008
This paper aims at explaining the differences in valuation of banking firms in Russia through the impact of selected elements of corporate governance. We rely upon value-based management theory to test the hypothesis that expenses on corporate governance
Bokov, V., Vernikov, A.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Better Board Education for Better Leadership and Management in the Health Sectors of Low and Middle Income Countries

open access: yesFrontiers in Public Health, 2019
Board member education must be elevated within the curricula of leadership development programming in Low and Middle Income Countries (LMICs) across the globe.
Godfrey Sikipa   +3 more
doaj   +1 more source

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