Results 71 to 80 of about 738,099 (338)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Nuevo mundo - Mundos Nuevos, 2019 This article studies the Culture Adviser of the Government Board, examining the man behind this position, his coordination with the governmental cultural apparatus, his trajectory in the vagaries of official politics and the ideological conflicts that ...
Matías Alvarado Leyton
doaj +1 more source
Making sense of co-operative governance: competing models and tensions
, 2002 This paper focuses on how cooperatives and mutual associations are governed. At the heart of these arrangements is an organisation's governing body or board.
Cornforth, Chris
core
Differential market valuations of board busyness across alternative banking models [PDF]
, 2018 This study comparatively assesses the influence of board busyness (i.e., multiple directorships of outside directors) on stock market valuations of both Islamic and conventional banks.
Elnahas, Marwa +3 more
core +4 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Investigating the Effective Factors on Participation of the Board of Directors in Decision Makings of the Industrial Cooperatives of Khoram Abad City [PDF]
تعاون و کشاورزی, 2011 Cooperative companies are partnership organizations and their indicative mark is democratic participation of members in planning & decision makings involved in governing the company’s affairs.
H Givarian, M. R Mandjin, F Falahpouri
doaj
Governing and Governance: A Social Housing Case Study [PDF]
This research project concerns the role of members of governing boards of formerly public assets, where these assets are transferred to a private or quasi-public organisation.
Dave Cowan +2 more
core
A Framework for Analyzing Nonprofit Governance and Accountability Policies and Strategies [PDF]
, 2006 This paper presents a framework for analyzing the sprawling topic of nonprofit governance and accountability. It distinguishes various accountability-generating mechanisms and actors, including the unit-level governing board; government policies aimed at
Mark H. Moore, William P. Ryan
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source