Results 81 to 90 of about 4,999,446 (322)
Synchronised firing patterns in a random network of adaptive exponential integrate-and-fire neuron model [PDF]
Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: CNPq, CAPES, and FAPESP (2011/19296-1 and 2015/07311-7).
Baptista, M.S. +7 more
core +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Enabling AI capabilities in government agencies: A study of determinants for European municipalities
Patrick Mikalef +7 more
semanticscholar +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Digital Government and Public Health
Digital government is typically defined as the production and delivery of information and services inside government and between government and the public using a range of information and communication technologies.
Jane E. Fountain
doaj
How do government agencies use evidence? [PDF]
Executive summary: Significant research gaps remain in our understanding about what happens in side government agencies in relation to the production, commissioning, assessment and incorporation of research-based evidence into their policy advice and ...
Brian Head
core
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Insourcing Functions Performed by Federal Contractors: Legal Issues [PDF]
[Excerpt] While agencies are prohibited by federal law and policy from contracting out functions that are “inherently governmental,” other functions could potentially be contracted out.
Manuel, Kate M, Maskell, Jack
core +2 more sources
Discretionary Authority and Prioritizing in Government Agencies
Government agencies have a certain freedom to choose among different possible courses of action. This article studies agency decision making on priorities in a principal–agent framework with multiple tasks. Agency leadership has discretion over part of
M. Schinkel, L. Tóth, Jan Tuinstra
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

