Results 61 to 70 of about 268,036 (312)
Results-Oriented Government: Practices That Can Help Enhance and Sustain Collaboration among Federal Agencies [PDF]
, 2005 A letter report issued by the Government Accountability Office with an abstract that begins "The federal government faces a series of challenges in the 21st century that will be difficult, if not impossible, for any single agency to address alone.
United States. Government Accountability Office.
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Indian Journal of Community Medicine, 1996 Research Question: What is the level of Public awareness on AIDS in a rural community and to what extent the government and non-government agencies have played their role in creating the awareness?
Balagnesh G +3 more
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
How do government agencies use evidence? [PDF]
, 2013 Executive summary: Significant research gaps remain in our understanding about what happens in side government agencies in relation to the production, commissioning, assessment and incorporation of research-based evidence into their policy advice and ...
Brian Head
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Electronic Government: Federal Agencies Continue to Invest in Smart Card Technology [PDF]
, 2004 A letter report issued by the Government Accountability Office with an abstract that begins "Smart cards--plastic devices about the size of a credit card--use integrated circuit chips to store and process data, much like a computer.
United States. Government Accountability Office.
core
, 2022 This study focuses on the Swedish public information programme Anslagstavlan, a unique audiovisual communication tool for Swedish government agencies since 1972 and an important part of Sweden’s audiovisual cultural heritage.
Emil Stjernholm
core +1 more source