Results 41 to 50 of about 163,321 (262)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An Empirical Comparison of Environmental Behaviors in China’s Public and Private Sectors

open access: yesProblemy Ekorozwoju, 2019
The distinctive public–private sector segmentation in China provides a unique opportunity to assess the impacts of environmental education. Considering that the ideological education of ecological civilization has long been mandatorily enforced in the ...
Yu Yang, Shizhi Huang, Xingting Huang
doaj  

The Strategies Analysis of Corporate University in the Government Agencies in Indonesia

open access: yesJurnal Wacana Kinerja, 2022
Changes in the world's landscape with massive digital developments affect learning and development strategies of human resources in every organization, including the Government Agencies.
Perdhana Ari Sudewo
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Survey on Public Awareness On AIDS- Role Of Government And Non Government Agencies In A Rural South Indian Community

open access: yesIndian Journal of Community Medicine, 1996
Research Question: What is the level of Public awareness on AIDS in a rural community and to what extent the government and non-government agencies have played their role in creating the awareness?
Balagnesh G   +3 more
doaj  

Design and development of wisdom-based organization model in government agencies [PDF]

open access: yesمدیریت دولتی, 2015
The importance of wisdom in managerial and organizational issues is growing. Wisdom, in addition to being the rational and moral judgment, is the most important success factor for organization.
Morteza Moradi
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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