Results 51 to 60 of about 163,321 (262)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Government Agencies Promotion of Women Entrepreneurship in India [PDF]
Pandian Journal of Women's StudiesWomen are the major source of manpower in any society. If any scheme aimed at the economic development of a nation without women will be uneven without involving them who constitute half of the world's population.
Dr. K. K. Thanammal
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Jurnal Akuntansi Aktual, 2019 The successful implementation of accrual-based GovernmentAccounting Standard is a very important thing that will have an impact on performance accountability of government agencies, then it is necessary for the identification of the factors that can ...
Ajhar ., Akram ., Endar Pituringsih
doaj
Feasibility of the Implementation of Activity-Based Costing (ABC) in Operational Budgeting of Government Agencies (A Case Study of Government Agencies of Isfahan Province) [PDF]
حسابداری سلامت, 2012 Introduction: This research investigated the factors affecting implementation of activity based costing (ABC) in operational budgeting of government agencies in Isfahan province.
D. Foroghi +2 more
doaj
Defending Leningrad (1941–1944)
Управленческое консультирование, 2019 The article is devoted to the analysis of the activities of the NKVD extermination battalions of the Leningrad Region in the battle for Leningrad in the period from 1941 to 1944.
V. P. Gridnev
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Ecology and Society, 2016 Successful natural resource management is dependent on effective knowledge exchange and utilization. Local/traditional/indigenous knowledge derived from place-based experience and scientific knowledge generated by systematic inquiry are the most commonly
Forrest Fleischman, David D. Briske
doaj +1 more source