Results 51 to 60 of about 1,641,397 (256)

Services to Industry by Libraries of Federal Government Agencies [PDF]

open access: yes, 1966
published or submitted for ...
Gray, Dwight E., Johnson, J. Burlin
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Survey on Public Awareness On AIDS- Role Of Government And Non Government Agencies In A Rural South Indian Community

open access: yesIndian Journal of Community Medicine, 1996
Research Question: What is the level of Public awareness on AIDS in a rural community and to what extent the government and non-government agencies have played their role in creating the awareness?
Balagnesh G   +3 more
doaj  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

ESCO Project for Buildings of Government Agencies in Thailand

open access: yesMATEC Web of Conferences, 2016
In Thailand, Department of Alternative Energy Development and Efficiency (DEDE) have organized the ESCO project to promote and encourage the use of machinery, materials and equipment having high efficiency for government buildings.
Prukvilailert Monchai, Wangskarn Prapat
doaj   +1 more source

Critique [of Racism and the Canadian State by Daiva K. Stasiulis] [PDF]

open access: yes, 1985
Stasiulis\u27s two-part essay offers a critique of the policies on immigration and racism pursued by the Canadian government during the past decade or so.
Hoglund, A. William
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

40 Years of FOIA, 20 Years of Delay: Oldest Pending Freedom of Information Requests Date Back to the 1980s [PDF]

open access: yes, 2007
Presents findings from the Knight Open Government Survey, which surveys government offices and agencies on the status of their public information requests, and finds that extensive backlogs ...
Catherine Nielsen
core  

Modernisation, managerialism and the culture wars: the reshaping of the local welfare state in England [PDF]

open access: yes, 2004
The story of local government over the last few decades is often summarised in the assertion that there has been a move away from institutional authority embodied in the structures of councils towards more complex networks of local governance ...
Cochrane, Allan
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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