Results 31 to 40 of about 1,641,397 (256)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Democratic Oversight of Government Hacking by Intelligence Agencies
Weizenbaum Journal of the Digital SocietyRegulating intelligence services is a challenge for modern societies worldwide. Their very modus operandi relies on tight secrecy protocols for the information gathered, internationally and domestically.
André Ramiro
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Ceiling and visibility instrumentation within government agencies [PDF]
, 1980 The key systems requirements for ceilometer systems are described. The following items are included: range must be 10,000 ft.; laser emission must conform to the bureau of radiological health class I performance; system must detect two lowest cloud ...
Bonner, R. S.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Funding Gaps and Government Shutdowns: CRS Experts [PDF]
, 2011 [Excerpt] In the event of a funding gap, the potential impacts of a government shutdown will depend on a program’s or agency’s specific circumstances and how relevant law is interpreted.
Brass, Clinton T
core +1 more source
Independent Agencies: Government’s Scourge or Salvation? [PDF]
, 1988 This symposium invites reflection on a number of important questions concerning the independence of the independent regulatory agencies. Three such questions are briefly examined in this essay: First, what is the nature of an independent agency?
Peters, Aulana L.
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Optimizing The Riparian Buffer: Harold Brook In The Skaneateles Lake Watershed, New York [PDF]
, 2002 The use of riparian land buffers to protect water quality for human consumption and wildlife habitat has become an important conservation tool of both government and non-government agencies.
Jon M. Conrad +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source