Results 81 to 90 of about 2,014,689 (307)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A Decade of Changing Pattern of Poverty in Great Britain [PDF]
It has been noted in the literature that failure to meet the target set by government for reducing the headcount ratio of child poverty in Britain is partly due to the success of government policy in generating economic growth.
Alvaro Angeriz, Shanti Chakravarty
core
Stop the Foreclosure Crisis: Make Wall Street Banks Pay [PDF]
, 2010 [Excerpt] Owning a home used to symbolize what it means to achieve the American Dream. But for millions of homeowners, that dream was dashed by the abuse, fraud and lawlessness of Wall Street banks.
AFL-CIO
core +1 more source
Building Failure and Collapse in Nigeria: the Influence of the Informal Sector [PDF]
, 2010 The occurrence of building failure and collapse has become a major issue of concern in the development of this nation as the magnitudes of this incident are becoming very alarming.
Fagbenle, Olabosipo I. +1 more
core +1 more source
Corporate governance and Corporate Failure
2nd Annual International Conferences on Accounting and Finance (AF 2012), 2012 AbstractThe purpose of this research is to examine the influence of corporate governance characteristics on the corporate failure of listed companies in Sri Lanka. This study utilized publicly available data from annual reports of a sample of 70 failed firms and a sample of matched 70 non failed firms listed on Colombo stock market for a period ...
Lakshan, A.M.I., Wijekoon, W.M.H.N.
openaire +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Government Failure and Market Failure: On the Inefficiency of Environmental and Energy Policy [PDF]
In this essay, we describe some important themes in energy and environmental policy. There are two main reasons for our interest in these policies. First, such policies will likely be important in the coming decades as issues related to climate change ...
Anthoff, David, Hahn, Robert W.
core +1 more source
Situating the transient user: overcoming challenges in the design of e-government systems [PDF]
, 2005 e-Government systems present new challenges for user involvement in the design process. Existing user-centred and participatory design methodologies were mainly developed for situations where a user is in the workplace.
Inglesant, PG, Sasse, MA
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source