Results 71 to 80 of about 2,014,689 (307)
An actor-network theory (ANT) approach to Turkish e-government gateway initiative [PDF]
, 2009 There are various models proposed in the literature to analyze trajectories of e-Government projects in terms of success and failure. Yet, only the Actor-Network Theory (ANT) perspective (Heeks and Stanforth, 2007) considers the interaction factors among
Aykac, D. Selcen O. +4 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Failed States Status in Contemporary International Law [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2013 Since the end of the cold war, the International Community has become increasingly preoccupied with a phenomenon giving rise to a wide range of humanitarian, legal and security strains generally known as ‘State failure’.
Aramesh Shahbazi, Khadijeh Javadi Sharif
doaj
Government Intervention as an Optimal Response to Government (not Market!) Failure [PDF]
This paper provides a theory of government intervention, such as government ownership, regulation, mandatory public schooling, subsidies, and industrial policy, as an optimal policy response due to the inability to commit not to expropriate private ...
Adriano Rampini, Alberto Bisin
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The perils of semi-presidentialism. Are they exaggerated? [PDF]
, 2008 There is a standard academic consensus that semi-presidentialism is perilous for new democracies. In particular, this is because semi-presidential countries run the risk of experiencing difficult periods of ‘cohabitation’ between a president and a prime ...
Elgie, Robert
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Remaking Local Government: Success and Failure Under Indiana’s Government Modernization Act
Journal of Public and Nonprofit Affairs, 2017 During the period of 2008 to 2012, four consolidation attempts occurred under Indiana’s Government Modernization Act: two proposing city–county consolidation and two proposing town–township consolidation.
Charles D. Taylor +2 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Public and private roles in road infrastructure: an exploration of market failure, public instruments and government failure [PDF]
Starting with a 'greenfield' situation, we discuss reasons for market failure in road infrastructure provision. We show why it may not be optimal from a welfare perspective to leave road provision fully to the market and government intervention in this ...
Mark Lijesen, Victoria Shestalova
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