Results 51 to 60 of about 271,411 (302)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
AI in the Government: Responses to Failures
Artificial Intelligence (AI) is pervading the government and transforming how public services are provided to consumers—from allocation of government benefits to enforcement of the law, monitoring of risks, and provision of services. Despite technological improvements, AI systems are fallible and may err.
Chiara Longoni, Luca Cian, Ellie Kyung
openaire +1 more source
The impact of critical success factors on government IT projects : a case study of the Defence Information Infrastructure Programme [PDF]
Government IT mega-projects often end in costly failure, despite attempts to identify those Critical Success Factors (CSFs) that lead to project success.
Maddison, A
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Objetivo: Este artículo pretende aportar al debate sobre la participación pública y privada en la provisión de servicios de salud y discutir los aspectos principales de las reformas de salud en Colombia en el contexto internacional y algunos de sus ...
Gloria Molina M +1 more
doaj
“Dream” and Poverty Alleviation
This research is motivated by the failure of Indonesian government in implementing its poverty alleviation. Poverty rate in Indonesia does not decrease although the government has implemented a complete strategy to address the problem.
Pajar Hatma Indra Jaya
doaj +1 more source
The anatomy of government failure
Government failure is a much bigger problem than its contemporary treatment implies. Setting aside natural disasters, most of the great catastrophes of human history have been government failures of one sort or another.
Keech, William R., Munger, Michael
core +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
State Collapse: Government Failure in Gaddafi's Libya
This article discusses the background and conditions of Libya before and during the reign of Muammar al-Gaddafi, which ended with the fall of his regime in 2011. Libya has a strong economy thanks to its oil resources, but Gaddafi's rule was characterized
Carelia Pradita Putri Hariyanti +2 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

