Results 71 to 80 of about 306,287 (257)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Industrial development in developing countries and the role of government interventions

open access: yesPSL Quarterly Review, 2013
The work argues that while export orientation (in the sense of providing neutral incentives between foreign and domestic markets) is desirable, the experience of successful industrialisers does not support the minimalist government role prescribed.
S. LALL, G. KELL
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Impact of the digital economy on low carbon sustainability evidence from the Yellow River Basin

open access: yesFrontiers in Energy Research
As the digital economy increasingly dominates a substantial portion of the national economy, comprehending its role in promoting sustainable development has become an imperative research question—particularly in the context of the Yellow River Basin ...
Gaofei Wang, Qingwen Yuan, Yong Jiao
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Pricing and Competition in Green Supply Chains Under Government Intervention [PDF]

open access: yesInternational Journal of Industrial Engineering and Production Research
The demand for green products has increased in the past few years due to the heightened awareness of environmental issues and the increasing use of green products by consumers. Thus, choosing the best strategy for green product manufacturers is essential.
Mojtaba NowrouziFasih   +2 more
doaj  

Evolutionary Game Study of the Cooperation Mode Between Renewable Energy Generation Enterprises and Energy Storage Companies Considering Government Intervention

open access: yesZhongguo dianli
Driven by the policy of new energy distribution and storage, renewable energy generation enterprises are equipped with energy storage facilities to improve the stability of energy supply, but the actual utilization efficiency of energy storage power ...
Xiaoyan ZOU, Ruihong ZHANG
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Systems thinking in local government: intervention design and adaptation in a community-based study. [PDF]

open access: yesHealth Res Policy Syst, 2023
Felmingham T   +9 more
europepmc   +1 more source

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