Results 121 to 130 of about 1,962,391 (308)
Maryland: Round 1 - State Level Field Network Study of the Implementation of the Affordable Care Act [PDF]
, 2014 This report is part of a series of 21 state and regional studies examining the rollout of the ACA. The national network -- with 36 states and 61 researchers -- is led by the Rockefeller Institute of Government, the public policy research arm of the State
Jocelyn M. Johnston
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Understanding Water Rights in Alaska [PDF]
, 2017 Alaska’s state constitution defines water as a public resource, but no one has automatic rights to use water.1 The constitution and Alaska law allow the state government to decide who can use water, how much they can use, and for what.
Leask, Linda, Lowe, Marie
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Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Prudent Investors: The Asset Allocation of Public Pension Plans [PDF]
After 2000, the vast majority of defined benefit (DB) pension plans encountered a decrease in their funding ratios, largely due to a drop in asset prices. It is possible that public sector pension plans may have acted imprudently by chasing returns, once
Christian E. Weller, Jeffrey Wenger
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Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
The Role of Local Government in Crime Prevention: An Overview [PDF]
, 2006 In Australia local government has played a key role in pro-active crime reduction, with it since 1980s partnering with different organisations at both state and local levels to address causes of offending. Crime prevention policies developed by state and
Cherney, Adrian
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
In its delivery of new aircraft carriers, the MoD has sacrificed short term affordability for long term value for money, a decision that may also leave the UK with a reduced defence capability. [PDF]
Like most other government departments, the Ministry of Defence has not been spared George Osborne’s axe, and plans to procure two new large aircraft carriers have been significantly affected.
Brown, Chris
core +1 more source