Results 111 to 120 of about 1,962,391 (308)

Newspaper of the university of alaska southeast juneau campus [PDF]

open access: yes, 1990
Instructors win arbitration case; teams unsettled -- Tanning salon plans to offer UAS discount -- New library pleases students -- USUAS to undergo face lift -- Student government computer disappears -- Finnish exchange student is never homesick ...

core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Minnesota: Individual State Report - State Level Field Network Study of the Implementation of the Affordable Care Act [PDF]

open access: yes, 2015
This report is part of a series of 21 state and regional studies examining the rollout of the ACA. The national network -- with 36 states and 61 researchers -- is led by the Rockefeller Institute of Government, the public policy research arm of the State
Donna Spencer   +3 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Assessing violence and injury prevention plans, strategies and indicators in eighteen Pacific Islands countries: an environmental scanResearch in context

open access: yesThe Lancet Regional Health. Western Pacific
Summary: Background: Similar to many other resource poor settings, due to competing priorities, injury is often neglected in the Pacific Islands despite being a prevalent cause of death and disability.
Rachel Baffsky   +5 more
doaj   +1 more source

It would be careless for the government to have to re-openbenefit indexation [PDF]

open access: yes, 2012
As the government reportedly plans to freeze most social security benefits for two years, before uprating them in line with wages rather than prices, Professor Deborah Mabbett investigates the politics of ...
Mabbett, Deborah
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Visualizing and Assessing Acceptance Sampling Plans: The R Package AcceptanceSampling

open access: yesJournal of Statistical Software, 2008
Manufacturers and government agencies frequently use acceptance sampling to decide whether a lot from a supplier or exporting country should be accepted or rejected.
Andreas Kiermeier
doaj  

The Structure of 401(k) Fees [PDF]

open access: yes
Increasingly, people are depending on 401(k) and similar defined contribution plans sponsored by their employers for their retirement income. As a result, participants in these plans also are paying more of their plans’ costs, ranging from administration
Dan Muldoon   +2 more
core   +1 more source

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