Results 51 to 60 of about 164,460 (261)

An analysis of problem in composing of tsunami contingency plan in Padang City

open access: yesMATEC Web of Conferences, 2018
Padang city is one of the most vulnerable areas of an earthquake potentially tsunami on the west coast of Sumatra Island. The government should formulate policies to minimize the impact of the disaster. The government and all relevant stakeholders should
Alhadi Zikri   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

How Government-Backed Registered Retirement Savings Plans Impact Canadians’ Tax-Free Savings Account:

open access: yesJournal of Social Equity and Public Administration
Personal savings can help cushion financial difficulties and reduce the need to apply for government assistance. This study examined who benefits the most and the least from the government-supported Registered Retirement Savings Plan (RRSP) and Tax-Free ...
Gino Biaou, Étienne Charbonneau
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mainstreaming HIV/AIDS in Gauteng urban municipalities: A bridge too far?

open access: yesCommonwealth Journal of Local Governance, 2010
Local government in South Africa, or ‘developmental local government’ as the lowest tier of government is often called (RSA 1998), carries the mandate of executing national development priorities of the country, as empowered by the constitution (RSA 1996)
Francis Kintu
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

AS POLÍTICAS SOCIAIS NOS PLANOS DE GOVERNO DOS PRESIDENCIÁVEIS 2018 NO BRASIL E A MÍDIA

open access: yesRevista de Políticas Públicas, 2019
The present research aimed to analyze and understand the place of social policies in the government plans presented by the presidential candidates in the 2018 elections in Brazil and the important role of the media in this interlocution.
Juliana Cândido Matias   +1 more
doaj  

PENGEMBANGAN 24 DESTINASI WISATA BAHARI KABUPATEN ENDE

open access: yesJurnal Kawistara, 2013
There are 24 marine tourism destinations in Ende District that have not been managed well enough. To improve tourism development, some management strategies should be taken by stakeholders.
Josef Alfonsius Gadi Djou
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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