Results 71 to 80 of about 1,962,391 (308)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Aid, ownership, and coordination in the health sector in Ethiopia
Development Studies Research, 2018 The Government of Ethiopia is seen as a owner of its national programs and policies and thus also as a strong coordinator of the foreign aid it receives.
Shumey B. Teshome, Paul Hoebink
doaj +1 more source
Annual Survey of Public Pensions: State- and Locally- Administered Defined Benefit Data Summary Report: 2013 [PDF]
, 2015 [Excerpt] This publication presents data on state- and locally- administered public pension systems based on information collected from the 2013 Survey of Public Pensions: State- and Locally-Administered Defined Benefit Data.
Vidal, Phillip
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Major challenges in developing a successful e-government: A review on the Sultanate of Oman
Journal of King Saud University: Computer and Information Sciences, 2015 The technological development has turned the government policies and strategies toward e-government. The e-government is considered the primary tool to facilitate the access of the citizens to various services.
Mohammad A. Sarrayrih, B. Sriram
doaj +1 more source
A report to iwi on the kaupapa Māori environmental outcomes and indicators kete [PDF]
, 2009 Tangata whenua in Aotearoa have been largely excluded from participation in local government planning since colonisation, but tikanga and Māori values have for the past two decades been acknowledged in resource management and local government ...
Jefferies, Richard, Kennedy, Nathan
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Government plans in the 2016 and 2021 Peruvian presidential elections: A natural language processing analysis of the health chapters. [PDF]
Wellcome Open Res, 2021 Carrillo-Larco RM +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Impact of Government Policies on the Inflation Rate in Iran: an Application of Learning Process in the Framework of Rational Expectations [PDF]
پژوهشهای اقتصادی, 2013 Today, policymakers and economists use widely rational expectations (RE) in monetary, financial and regulatory policies to improve their country economic performance.
Kazem Farahmand Gelyan +1 more
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