Results 101 to 110 of about 216,366 (291)

The Spatial Spillover Effects of Environmental Regulation and Regional Energy Efficiency and Their Interactions under Local Government Competition in China [PDF]

, 2022
Fangyu Ju, Mengfan Ke
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Australian access to FDA-approved breakthrough therapy designation medicines: a 10-year review

Journal of Pharmaceutical Policy and Practice
Background Regulatory pathways adopted by the United States Food Drug and Administration (FDA) and Australian Therapeutic Goods Administration (TGA) enable expedited approval of medicines that are thought to offer significant clinical advantage over ...
Senthil Lingaratnam, Safeera Yasmeen Hussainy, Alexandra Murphy, Cale Perrin, Melbin Samuvel, Elahe Mehrvarz, Chiao Xin Lim, John Zalcberg   +7 more
doaj   +1 more source

Political economy of the US financial crisis 2007-2009 [PDF]

Financial Theory and Practice, 2011
The emphasis of this paper is on the political economy of the subprime mortgage crisis in the United States and how the policy makers contributed to it through their legislation and regulations, made under the rising influence of interest groups and the ...
Vuk Vuković
doaj  

Government Regulation, Executive Overconfidence, and Carbon Information Disclosure: Evidence From China. [PDF]

Front Psychol, 2021
He R, Cheng Y, Zhou M, Liu J, Yang Q.
europepmc   +1 more source

Government regulations and sickle cell trait [letter] [PDF]

, 1983
Cameron Bf, D. J. Smith, Barbara Cody
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Analysis of foreign experience of regulating the sphere of information services in the conditions of digitalization

Новые технологии, 2018
The article considers various approaches to regulation of information services in the conditions of digitalization. It indicates the presence of two conceptual approaches to identifying areas of support for the development of information services ...
N. S. Shitukhina
doaj  

Optimizing the Regulation of Nursing in the Asian Context: Development and Application of a Legal Framework

Asian Nursing Research
s u m m a r y: Purpose: It is essential to regulate nursing to protect the population's health. As regulation constantly changes in response to societal trends, periodic reviews of nursing regulations become imperative.
Sungkyoung Choi, Won Lee
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source