Results 81 to 90 of about 304,684 (307)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Government and Health Outcomes [PDF]
In this paper, I summarize the results of empirical studies in the areas of schooling and health, public programs and infant mortality, and government regulation of teenage smoking. My review is selective and is based on my own research.
Michael Grossman
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Warta Pengabdian Andalas, 2016 Applicable local Pariaman Number 20 in 2012 About Providence health coverage Sabiduak Sadayuang (JK-SS) was established by the Government of Pariaman as a policy area in order to improve the policies of the Central Government to enact public health ...
Delfina Gusman +4 more
doaj
Governance and Regulation Issues: Corporate Governance and Bank Regulation
, 2014 The global financial crisis has generated, and brought up new challenges in the management and regulation of the banking system. Besides, it raised the topicality of the problems existed before. Therefore the future prospects of overcoming the crisis to a large extent depend on direction of modern financial system development, and a new paradigm of ...
Kostiuk, Oleksandr Mykolaiovych +2 more
openaire +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Policy Making Without Legislating; the Self-regulation of Commercial Property Leasing [PDF]
The terms of a commercial property lease covers aspects such as rent, alterations to premises and the ability to leave; consequently they have a significant impact on cash flow and the ability of a business to develop.
Cathy Hughes, Neil Crosby
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Risk Perceptions in Regulation, Tort Liability, and the Market
, 1991 article published in a journal of administrative lawRisk regulations are generally based on a stylized view of the behavior of the individuals affected by the regulation.
Viscusi, W. Kip
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Journal of Marine Science and EngineeringVarious types of tidal barriers are used in estuaries to reduce saltwater intrusion and regulate freshwater discharge, but they often alter the physicochemical environment and faunal composition.
Sorcha Cronin-O’Reilly +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Economic Regulation: Recentralisation of Power or Improved Quality of Regulation? [PDF]
The October 2009 Government Statement on Economic Regulation proposes a number of sensible reforms that are likely to improve regulatory performance in energy, airports, telecommunications, postal services and transport. However, the Government Statement
PAUL K. GORECKI
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