Results 81 to 90 of about 1,745,962 (311)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Journal of Marine Science and EngineeringVarious types of tidal barriers are used in estuaries to reduce saltwater intrusion and regulate freshwater discharge, but they often alter the physicochemical environment and faunal composition.
Sorcha Cronin-O’Reilly +4 more
doaj +1 more source
Privatization Incentives – A Wage Bargaining Approach [PDF]
We analyze the incentives of a government to privatize a state owned firm. Assumingprice cap regulation, a unionized labor market and wage bargaining the government’sgains from privatization depend on two effects.
Andreas Kuhlmann
core
, 2006 The ‘standard model’ of electricity reform has been refined in many countries but not extended to others. Government is supplanting the role of regulation.
Littlechild, Stephen C.
core +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On the issue of self-regulation of the financial markets
Путеводитель предпринимателя, 2020 The article considers the main provisions of the new draft of the project «On self-regulatory organizations on the financial markets» in terms of the basic concept of self-regulation, the existing approaches to the regulation of economic activity and the
Yu. S. Bugaev, S. I. Rybakov
doaj
An overview and visual analysis of research on government regulation in healthcare. [PDF]
Front Public Health, 2023 Qi M, Ren J.
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Government regulation strategies for inhibiting opportunistic behaviors in construction projects. [PDF]
Heliyon, 2023 Cui L, Liu G, Luo L.
europepmc +1 more source