Results 61 to 70 of about 222,637 (260)

GOVERNMENT REGULATION OF HOUSING.

open access: yesХабаршысы. Экономика сериясы, 2015
В статье рассматривается современное состояние жилищного сектора и роль государственных программ в обеспечении жильем народа Республики Казахстан.
S. Orakbaeva
doaj  

STRUCTURE OF THE MARKET OF INNOVATIVE PRODUCTS: APPROACH TO ASSESSING THE IMPACT ON EFFICIENCY [PDF]

open access: yesKrymskij Naučnyj Vestnik, 2015
The formation of innovation policy innovative economy is impossible without an understanding of the conceptual basis of the efficiency of production of innovative products.
Anna Elagina
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Sosialisasi Peraturan Daerah Kota Pariaman Nomor 20 Tahun 2012 Tentang Jaminan Kesehatan Sabiduak- Sadayuang (JK-SS) Dalam Rangka Memberikan Jaminan Kesehatan Masyarakat Di Kecamatan Pariaman Tengah, Kota Pariaman

open access: yesWarta Pengabdian Andalas, 2016
Applicable local Pariaman Number 20 in 2012 About Providence health coverage Sabiduak Sadayuang (JK-SS) was established by the Government of Pariaman as a policy area in order to improve the policies of the Central Government to enact public health ...
Delfina Gusman   +4 more
doaj  

Tidal Exclusion Barriers Fragment an Invertebrate Community into Taxonomically and Functionally Distinct Estuarine and Wetland Assemblages

open access: yesJournal of Marine Science and Engineering
Various types of tidal barriers are used in estuaries to reduce saltwater intrusion and regulate freshwater discharge, but they often alter the physicochemical environment and faunal composition.
Sorcha Cronin-O’Reilly   +4 more
doaj   +1 more source

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