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Non-small cell lung cancer (NSCLC) accounts for ~85% of lung cancer cases and remains the leading cause of cancer-related mortality worldwide. Despite advances in targeted therapies, early diagnosis and prediction of treatment response remain major ...
Pablo Martin-Lopez +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Macroeconomic effects of regulation and deregulation
The role of government in market economies is being discussed for more than two centuries. This problem is particularly topical in most transition countries, where the transition from a totalitarian political system and controlled economy to a multiparty,
Marija Lakićević +2 more
doaj +4 more sources
Viewpoint of COVID-19 in Africa and Latin America
The spread of COVID-19 across the African continent and Latin American region is of great concern due to several influencing factors. Large and densely populated areas and townships with widespread poverty and high migration are the most vulnerable ...
Dominique Fournier, Ernest Herbert
doaj +1 more source
How to Improve Farmers’ Green Production Level in a Targeted Manner?
Improving farmers’ green production behavior can guarantee food safety at the source. In recent years, a rising number of studies have focused on food safety management and have provided general regulation recommendations. Unlike many studies, this study
YanLi Yu +4 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Environmental Regulation: Can government regulate itself? [PDF]
Leading theories of regulation assume that governments regulate profit-maximizing firms: governments set rules, to which firms respond rationally in ways that constrain their behavior.
Konisky, David M., Teodoro, Manuel P.
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Northern Territory Government Photographer
Ted Egan, Administrator sitting with delegates and guest at the NT Expo presentations.Protocol Unit.Date:2005 ...
Northern Territory Government Photographer
core +4 more sources

