Results 71 to 80 of about 222,637 (260)
Governance and Regulation Issues: Corporate Governance and Bank Regulation
, 2014 The global financial crisis has generated, and brought up new challenges in the management and regulation of the banking system. Besides, it raised the topicality of the problems existed before. Therefore the future prospects of overcoming the crisis to a large extent depend on direction of modern financial system development, and a new paradigm of ...
Kostiuk, Oleksandr Mykolaiovych +2 more
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On the issue of self-regulation of the financial markets
Путеводитель предпринимателя, 2020 The article considers the main provisions of the new draft of the project «On self-regulatory organizations on the financial markets» in terms of the basic concept of self-regulation, the existing approaches to the regulation of economic activity and the
Yu. S. Bugaev, S. I. Rybakov
doaj
Вісник Житомирського державного технологічного університету: Серія: економіка, управління та адміністрування, 2019 In the period of radical reforms and socio-economic transformations in Ukraine, the formation of foreign policy aimed at close cooperation with other European countries, domestic scientists and practitioners should focus on the main priorities of ...
O.V. Orlova-Kurilova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Government regulation strategies for inhibiting opportunistic behaviors in construction projects. [PDF]
Heliyon, 2023 Cui L, Liu G, Luo L.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Evolutionary game theory and simulations based on doctor and patient medical malpractice under government regulation. [PDF]
Sci Rep, 2023 Song L, Yu Z, Fang J, He Q.
europepmc +1 more source