Results 181 to 190 of about 6,625,613 (395)
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
FEBS Open Bio, EarlyView.Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
Consensus Versus Incentives: A Skeptical Look at Regulatory Negotiation [PDF]
, 1994 Some recommendations are designed to improve the efficiency of public regulation. Incentive-based systems, for example, can make government policies more cost-effective. Other recommendations are disembodied law reforms, espoused without much concern for
Rose-Ackerman, Susan
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra +17 more
wiley +1 more source
Prices of Medicines a Case-Study on the impact of the rate-of-return regulation in the United Kingdom [PDF]
This work carries out an empirical evaluation of the impact of the main mechanism for regulating the prices of medicines in the UK on a variety of pharmaceutical price indices.
Joan Ramon Borrell Arque
core +1 more source
Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova +3 more
wiley +1 more source
State and non-state regulation in African protracted crises: governance without government? [PDF]
, 2008 Timothy Raeymaekers +2 more
openalex +1 more source
Translating Principles Into Practice in Regulation Theory [PDF]
Regulators must understand basic principles of regulation, to explain with credibility their decissions, to asess the universality of the proposals, to develop new solutions, etc.
Laffont, Jean-Jacques
core
PERLINDUNGAN HUKUM TERHADAP INDIKASI GEOGRAFIS SEBAGAI CIRI SUATU PRODUK DI TINJAU DARI UNDANG-UNDANG NOMOR 15 TAHUN 2001 TENTANG MEREK [PDF]
, 2006 The purpose of this legal writing are know the legal protection of geographical Indications as product characteristic in Indonesia that is observed from constitution number 15th, 2001 about trademark, so we will know the important of geographical ...
Gunarsih, Gunarsih
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos +11 more
wiley +1 more source
Patterns in Transvaginal Mesh Surgery After Government Regulation in the United States.
JAMA Surg, 2022 Lewicki P +5 more
europepmc +1 more source