Results 91 to 100 of about 12,375,765 (343)

Size and soft budget constraints [PDF]

, 2006
There is much evidence against the so-called "too big to fail" hypothesis in the case of bailouts to sub-national governments. We look at a model where districts of different size provide local public goods with positive spillovers.
Crivelli, Ernesto, Staal, Klaas
core   +5 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Long-Term Economic Effects of Structural Budget Reform Emphasizing the Rationalizing the Composition and Size of Government in Iran (Systemic Dynamics Approach)

برنامه‌ریزی و بودجه, 2021
The main purpose of this study is to simulate the long-term economic effects of government size on the economy and its expenditures combination based on Iran's budget structure over the next 20 years using the dynamic system of scenarios.
Mohammad Ghaffary Fard, Hossein Rezaei, Dawood Yousufzai   +2 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Effectiveness of Government Size on Economic Growth in Iran (by Boundaries Testing Approach) [PDF]

فصلنامه پژوهش‌های اقتصادی ایران, 2013
We analyse short-run and long-run effects of government size on the economic growth of Iran ,using 1353-90 time series .the results of estimation , by using of ARDL  and boundaries testing approach, indicate convergence of the dynamic model to the long ...
Behzad Alipour, Mehdi Pedram, Iman Charghanian   +2 more
doaj  

The optimal government size and economic growth: A comparative study between Malaysia and South Korea. [PDF]

Heliyon, 2023
Goh HH, Mohd Aznan MSB.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

How Harmful Is a High Share of Public Expenditure in GDP?

Economies
We aim to analyze the potential positive or negative effects of public expenditure on economic growth, as well as their determinants. To this goal, we use a simple theoretical model, which has the specificity to distinguish between public investment and ...
Séverine Menguy
doaj   +1 more source

Analyzing the Relationship Between Government Size and Unemployment Rate in Iran [PDF]

Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2011
This study investigates the relation between unemployment rate and Government Size in Iran. For that, we have used some VAR models, which include the following variables: government size, measured as total government outlays as a percentage of GDP ...
Ebrahim Ali Razini, Amir Reza Soori, Ahmad Tashkini   +2 more
doaj  

Nonlinear threshold approach for asymmetric effects of government size on economic growth in an emerging Asian economy: the Malaysian experience. [PDF]

Heliyon, 2022
Bin Mohd Aznan MS, Goh HH, Koong SS, Tan SH.   +3 more
europepmc   +1 more source