Results 111 to 120 of about 12,375,765 (343)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The size and growth of government spending [PDF]

open access: yes
This paper reviews the size and growth of government spending. Section I surveys the empirical evidence on the growth of government expenditures. First, a number of measurement issues are raised, including the definition of the public sector, the ...
Lindauer, David L.
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Effect of Government Size and Good Governance on Human Development by Using Geographical Weighted Regression [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2014
The main objective of this paper is to study the effect of government size and good governance on human development in different countries in 2000, 2005 and 2010.
Hadi Rafiee Darani, Naser Shahnooshi
doaj  

Government spending volatility and the size of nations [PDF]

open access: yes
This paper provides empirical evidence showing that smaller countries tend to have more volatile government spending for a sample of 160 countries from 1960 to 2000.
Furceri, Davide   +1 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Tamanho do Governo Brasileiro: Conceitos e Medidas [PDF]

open access: yesRAC: Revista de Administração Contemporânea, 2010
The purpose of this paper is to build a measure of government size for Brazil in terms of state-owned companies. We build the government size considering the federal government’s current expenditure (international measure) and the state-owned company’s ...
Vladimir Fernandes Maciel   +1 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Optimal size of central government and agglomeration [PDF]

open access: yes
Though the central government uses neither a transfer nor a regional allocation policy, it can affect the distribution of the population. This paper analyzes the optimal government policy and examines whether or not the government should take into ...
Akiyoshi Furukawa
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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