Results 101 to 110 of about 1,108,976 (316)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Improvements Needed to the Federal Procurement Data System-Next Generation [PDF]
, 2005 Correspondence issued by the Government Accountability Office with an abstract that begins "Federal government purchases of goods and services have grown to more than $300 billion annually. The Federal Procurement Data System-Next Generation (FPDS-NG) is
United States. Government Accountability Office.
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Local Government System in Japan
Èkonomika, Pedagogika i Pravo, 2016 The article is devoted to the issues of the activities of the local government of Japan. Particular attention is drawn to the legal framework and the material basis for the functioning of local self-government bodies.
Vladimir V. Redko
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Executive Summary. Conservation management plan for Government House and its precinct, Darwin
, 1998 Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).On 19 March 1996 Government House was declared a "heritage place" under the provisions of the Northern Territory Heritage Conservation Act, because of its
Forrest, Peter, Troppo Architects
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Service delivery review: a how to manual for local government [PDF]
, 2014 This resource aims to assist councils assess the services they provide for local communities. Service Delivery Review: A How to Manual for Local Government brings together advice, toolkits and templates to help councils regardless of size ...
Roberta Ryan +5 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Human Capital: DOD's National Security Personnel System Faces Implementation Challenges [PDF]
, 2005 A letter report issued by the Government Accountability Office with an abstract that begins "The Department of Defense's (DOD) new personnel system--the National Security Personnel System (NSPS)--will have far-reaching implications not just for DOD, but ...
United States. Government Accountability Office.
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Movement and dietary behaviours and mental health among university students: the Health@NUS study
BMC Public HealthIntroduction University years represent a crucial period in a student’s life, with mounting pressures on mental health and the formation of lifestyle habits that may endure into adulthood. This study examined the associations between movement and dietary
Shenglin Zheng +8 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source