Results 61 to 70 of about 771,198 (268)

A dataset of interprovincial food trade flows in China

open access: yesScientific Data
Understanding the food trading network is crucial for optimizing resource allocation, maintaining stability in the food system, and safeguarding food security.
Lan Luo   +7 more
doaj   +1 more source

Local Government System in Pakistan: Causes of bad Governance of Local Government System

open access: yesJournal of Social and Administrative Sciences, 2015
The local government is one of the vital organs of the state through which programs of development are formulated and implemented for the community. The democratically elected members at the local government level represented the community and advocate the interests of the community in the social and economic development of the area. The research paper
Sirajul Haq KANDHRO, Ghulam AKBER
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Management of Type 1 Plastic Bronchitis—A Pediatric Case Report

open access: yesClinical Case Reports
Plastic bronchitis (PB) is a rare and potentially fatal condition characterized by the formation of branching bronchial casts, leading to airway obstruction that can cause severe respiratory failure.
Aswathy Mathews, Amal Prazad
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

DESAIN OTONOMI DAERAH DALAM KERANGKA PENEGASAN SISTEM PEMERINTAHAN PRESIDENSIAL

open access: yesProgresif, 2019
This research is entitled “Design Of Regional Autonomy In The Affirmative Framewok Of Presidential Government Systems Affirmation:. This research is motivated by the decentralization of Indonesia which has unsymmetrical, because of the existence of ...
Rio Armanda Agustian
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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