Results 101 to 110 of about 24,865,421 (393)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Big Data, Algorithmic Governmentality and the Regulation of Pandemic Risk [PDF]
European Journal of Risk Regulation, 2019 This article investigates the rise of algorithmic disease surveillance systems as novel technologies of risk analysis utilised to regulate pandemic outbreaks in an era of big data. Critically, the article demonstrates how intensified efforts towards harnessing big data and the application of algorithmic processing techniques to enhance the real-time ...
openaire +1 more source
From Governmental Accounting to National Accounting: Implications on the Portuguese Central Government Deficit [PDF]
Based on the relevant differences between Governmental Accounting (GA/microeconomic perspective) and National Accounting (NA/macroeconomic perspective) this paper examines the main adjustments made in Portugal to the General Government Sector data ...
Maria Antónia Jesus, Susana Jorge
core
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Comparing clients’ satisfaction with governmental and private speechtherapy clinics of Ahvaz, Iran
مجله پژوهش در علوم توانبخشی, 2013 Introduction: Reaching ultimate therapeutic goals in rehabilitation discipline (especially, in speech therapy) requires a long-term process. Having through knowledge about the level of clients’ satisfaction may, thus, be important in achieving and ...
Peyman Zamani
doaj +1 more source
Philosophical Aspects of Big Data [PDF]
Big Data can generate, through inferences, new knowledge and perspectives. The paradigm that results from using Big Data creates new opportunities. Big Data has great influence at the governmental level, positively affecting society. These systems can be
Sfetcu, Nicolae
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SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Фінансово-кредитна діяльність: проблеми теорії та практики, 2019 Non-governmental organizations have a potential to meet social needs and perform important civil tasks. Non-governmental organizations make a significant impact to the social life in Poland.
A. M. Revko, A. V. Verbytska
doaj +1 more source