Results 31 to 40 of about 155,105 (260)
Racing through the Dutch Governmental Data Assemblage: A Postcolonial Data Studies Approach
Global Perspectives, 2020 This article is part of the Global Perspectives, Media and Communication special issue on “Media, Migration, and Nationalism,” guest-edited by Koen Leurs and Tomohisa Hirata. In line with the focus of this issue, we are interested in the ways in which open data is progressively used to construct indicators of the state’s performance in the form of race-
van Schie, Gerwin +2 more
openaire +2 more sources
From governing through data to governmentality through data: Artefacts, strategies and the digital turn [PDF]
European Educational Research Journal, 2015 The article argues that current discussions about governance through data in education can be fruitfully extended through: (1) the establishment of connections with wider debates about the role of commensuration processes and governmentality in the recreation of education systems; (2) greater emphasis on the ‘artefacts’ through which data ...
Souto-Otero, M., Beneito-Montagut, R.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Issues and Guiding Principles for Opening Governmental Judicial Research Data [PDF]
, 2012 The opening of data is considered to provide many benefits. However, opening up data by public bodies is a complex and ill-understood activity. Although many public bodies might be willing to open up their data, they lack any systematic guidance. In this paper, guidance is provided by investigating the publishing processes at the Dutch Research and ...
Zuiderwijk-van Eijk, A.M.G. (author) +5 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Enhancing the Usefulness of Open Governmental Data with Linked Data Viewing Techniques [PDF]
Proceedings of the Annual Hawaii International Conference on System Sciences, 2019 Open Governmental Data publishing has had mixed success. While many governmental bodies are publishing an increasing number of datasets online, the potential usefulness is rather low. This paper describes action research conducted within the context of the Dutch Cadastre’s open data platform.
Folmer, Erwin +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
IEEE Access, 2020 Linked Data is an innovative approach for publishing heterogeneous data sources on the web. As such, it can transcend the traditional confines of separate databases, as well as the confines of separate institutions.
Erwin Folmer +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source