Results 41 to 50 of about 23,968,964 (258)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
This study aimed to examine the effect of embracing the Health Belief Model (HBM) in governmental public health messages on social media during the coronavirus disease 2019 pandemic.
Rashed Alhaimer
doaj +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Linked Data is an innovative approach for publishing heterogeneous data sources on the web. As such, it can transcend the traditional confines of separate databases, as well as the confines of separate institutions.
Erwin Folmer +4 more
doaj +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
THE ELEMENTS OF THE APPLICATION OF THE EXPANDED RULE AS AN INPUT TO IMPROVE THE ENVIRONMENTAL SITUATION IN EGYPT - AN EMPIRICAL STUDY [PDF]
The research aims to study the concept of Environmental Governance and dimensions and effervescence and analysis of environmental government policies toward activating the participation of non-governmental organizations in carrying out environmental ...
Noman A. M. +3 more
doaj +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Comparison of the Safety Levels of Governmental and Non-Governmental Schools: Study in Yazd City, Iran, 2009 [PDF]
The school environment is an environment wherein a student spends one third of his life with teachers and other students. In the present study, the safety levels of governmental and non-governmental schools were studied and compared.
Gholam Hossein Halvani, Damon Ketabi
doaj +1 more source
Replication Data for: Global Climate Change Survey
The global climate, a shared resource, needs collaborative efforts worldwide. A behavioral science perspective can help to better understand the human factor, which is crucial in addressing climate change.
Chopra, Felix +3 more
core +1 more source

