Results 31 to 40 of about 71,655 (295)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Recent Developments of the Internal Credit in Romania

Scientific Papers Animal Science and Biotechnologies, 2023
The article presents the structure of the Romanian banking system and the evolution of internal credit (governmental and non-governmental). Both aspects are analyzed from the point of view of their progress, retrospectively on the one hand, and potential
Elena Claudia Sîrbulescu, Luminiţa Pîrvulescu, Mariana Chirilă, Daniel Chirilă   +3 more
doaj  

BOUNDING THROUGH TERRITORY: EUROPEAN UNION AND MULTI-LEVEL TERRITORIAL GOVERNANCE

Ankara Avrupa Çalışmaları Dergisi, 2022
This study discusses what implications territorial governance has on the governmental and territorial nature of the European Union (EU). The EU increasingly addresses governance on a territorial basis to improve its territorial integrity and coherence ...
Samet Yılmaz
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Addressing the needs of Ethiopia’s street homeless women of reproductive age in the health and social protection policy: a qualitative study

International Journal for Equity in Health, 2023
Introduction Globally, homelessness is a growing concern, and homeless women of reproductive age are particularly vulnerable to adverse physical, mental, and reproductive health conditions, including violence.
Kalkidan Yohannes, Mats Målqvist, Hannah Bradby, Yemane Berhane, Sibylle Herzig van Wees   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Investigating the Relationship between Corporate Governance Characteristics and Financing Decisions [PDF]

International Journal of Management, Accounting and Economics, 2016
This paper investigates the relationship between the components of corporate governance structure including board characteristics, ownership structure, and financial leverage in the companies listed on Tehran Stock Exchange.
Zeinab Azami
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

ANALYSIS OF THE BARRIERS LEADING TO FAILURE OF LAND CONSOLIDATION OF THE FIELDS [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2016
The biggest problem in transition from traditional agriculture to modern and up-to-date agriculture is the lack of land consolidation of the fields. The present study aimed to analyze the barriers to effective land consolidation of fields in the city of ...
Loghman RASHIDPOUR, Solieman RASOULI AZAR   +1 more
doaj