Results 141 to 150 of about 61,865 (283)

Bimekizumab efficacy and safety in Chinese patients with psoriasis in the BE SHINING Phase 3 study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In Chinese patients with moderate to severe plaque psoriasis, bimekizumab treatment was well tolerated and led to significantly higher clinical response rates versus placebo, including complete skin clearance. These findings were consistent with global studies and suggest that bimekizumab is an effective treatment option for Chinese people living with ...
Lin Cai, Xiao‐Yong Man, Jinyan Wang, Aihua Wei, Ying Chen, Delphine Deherder, Jun Gao, Bengt Hoepken, Weiwei Sun, Tingting Lei, Jianzhong Zhang, the BE SHINING Study Group   +11 more
wiley   +1 more source

Proces en verantwoording GPP module

, 2013
Dit document is één van de twee eindproducten voor de module Green Protorype Platform. In dit deel is te lezen hoe ons proces verlopen is en ook hoe we doelstellingen behaald hebben die vooraf gesteld zijn. Tot slot is een bondige beschrijving te lezen over urban farming.
Vreden, Coen van, Versteeg, Paul
openaire  

Bimekizumab efficacy using IHS4 outcomes in hidradenitis suppurativa: Results from BE HEARD I and II

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The majority of bimekizumab‐treated patients shifted from severe to mild and moderate IHS4 stages, and nearly 25% achieved an IHS4 of 0 by Week 48. Bimekizumab led to clinically meaningful improvements across IHS4 outcome measures. These data highlight an opportunity to address the need for effective treatments against draining tunnels.
Thrasyvoulos Tzellos, Evangelos J. Giamarellos‐Bourboulis, Kelsey R. van Straalen, Antonio Martorell, Brian Kirby, Afsaneh Alavi, Koremasa Hayama, Saakshi Khattri, Wayne Gulliver, Christopher J. Sayed, Leah Davis, Robert L. Rolleri, Christina Crater, Ingrid Pansar, Jérémy Lambert, Christos C. Zouboulis   +15 more
wiley   +1 more source

Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context

Journal of Integrative Plant Biology, EarlyView.
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac, Milica Milutinović, Dragana Matekalo, Neda Popović, Luka Petrović, Uroš Gašić, Marijana Skorić, Branislav Šiler, Tamara Lukić, Ana Stupar, Slavica Dmitrović, Jasmina Nestorović Živković, Biljana Filipović, Jelena Božunović, Miloš Todorović, Danijela Mišić   +15 more
wiley   +1 more source

Guidelines for good pharmacoepidemiology practices (GPP) [PDF]

Pharmacoepidemiology and Drug Safety, 2008
openaire   +2 more sources

Metabolomic and Single‐Cell Transcriptomic Analyses Shed Light on Secondary Metabolite Profiling and Potential Developmental Dynamics of Glandular Trichomes in Artemisia argyi

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant glandular trichomes (GTs) are characterised by their ability to synthesise and store abundant secondary metabolites of significant biological importance. The medicinal plant Artemisia argyi exhibits a dense covering of GTs, yet the precise metabolic compositions and the developmental molecular dynamics of A.
Shuting Dong, Hongyu Chen, Sijie Sun, Miaoxian Guo, Chao Sun, Shilin Chen, Hongmei Luo   +6 more
wiley   +1 more source

Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO2, light, water and minerals through their innate photosynthetic carbon assimilation machinery.
Xuan Sun, Xiuming Wu, Xun Jiang, Hongmei Huang, Aiguo Yang, Yiting Li, Zhenjun Fan, Aixia Chang, Changqing Yang   +8 more
wiley   +1 more source

Controls on water-carbon coupling shift from climate to vegetation structure in the Minjiang River Basin. [PDF]

Carbon Balance Manag
Lu G, Zhong Y, Liang Y, Yi Z, Shi Y, Tang Q, Liang Y.   +6 more
europepmc   +1 more source

Reducing the Sinapine Levels of Camelina sativa Seeds Through Targeted Genome Editing of REF1

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sinapine (O‐sinapoyl choline) is the major phenolic metabolite typically found in the oil‐rich seeds of Brassicaceae such as Camelina sativa and Brassica napus. It imparts a bitter taste to the seeds as a defence mechanism against herbivores, but it also renders them less palatable to livestock.
Amélie A. Kelly, Martin Fulda, Merle Aden, Ilka N. Abreu, Kirstin Feussner, Ivo Feussner   +5 more
wiley   +1 more source

Solar radiation differences drive karst sun and shade leaf carbon sink contribution shifts. [PDF]

Carbon Balance Manag
Du J, Wu L, Wei H, Chen D, Yang D, Xiong L, Xia Y.   +6 more
europepmc   +1 more source