Results 61 to 70 of about 994,861 (301)

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Quantification of the variation in percentage identity for protein sequence alignments

BMC Bioinformatics, 2006
Background Percentage Identity (PID) is frequently quoted in discussion of sequence alignments since it appears simple and easy to understand. However, although there are several different ways to calculate percentage identity and each may yield a ...
Raghava GPS, Barton Geoffrey J
doaj   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Giant Pulses with Nanosecond Time Resolution detected from the Crab Pulsar at 8.5 and 15.1 GHz [PDF]

, 2010
We present a study of shape, spectra and polarization properties of giant pulses (GPs) from the Crab pulsar at the very high frequencies of 8.5 and 15.1 GHz. Studies at 15.1 GHz were performed for the first time.
A. Jessner, A. V. Bilous, A. Zensus, Argyle, Baars, Cognard, Cordes, D. Graham, Dyks, Hankins, Hankins, Hankins, Hankins, Jessner, Johnston, Kinkhabwala, Knight, Kuzmin, Loehmer, Lundgren, Lyutikov, M. V. Popov, Moffett, Muslimov, O. A. Moshkina, Petrova, Petrova, Popov, Popov, Popov, Popov, Popov, Radhakrishnan, Rickett, Romani, Soglasnov, Staelin, V. A. Soglasnov, V. I. Kondratiev, von Hoensbroech, Wang, Weatherall, Wilson, Y. Y. Kovalev   +43 more
core   +3 more sources

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

La teoría del cambio: una herramienta para la planificación y la evaluación participativa en salud comunitaria

Gaceta Sanitaria, 2020
Resumen: Existe un creciente interés por encontrar respuestas innovadoras para evaluar intervenciones complejas en salud pública. En esta nota metodológica, se presenta la teoría del cambio como una herramienta útil para facilitar tanto la planificación ...
Viola Cassetti, Joan J. Paredes-Carbonell   +1 more
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Self‐Assisted Charge Storage‐Release Mechanism Enabling Flexible Design of Biomimetic Triboelectric Nanogenerators

Advanced Science, EarlyView.
Inspired by the mimosa, this study develops a flexible triboelectric nanogenerator with a novel microneedle array and battery‐mimetic architecture. The device introduces a spontaneous charge self‐regulation mechanism that confines the electric field below the air breakdown threshold, and achieves an outstanding charge density of 396.50 µC m−2 ...
Hanpeng Gao, Yamin Hu, Li Li, Ana Sofia Oliveira Henriques Moita, Xi Wang, Zong Meng, Zhiwu Han, Yan Liu   +7 more
wiley   +1 more source

Detecting Stops from GPS Trajectories: A Comparison of Different GPS Indicators for Raster Sampling Methods [PDF]

, 2017
With the increasing prevalence of GPS tracking capabilities on smartphones, GPS trajectories have proven to be useful for an extensive range of research topics.
Mcarthur, David P., Wang, Yang
core  

GPS monitoring of a steel box girder viaduct [PDF]

, 2012
Structural performance monitoring of bridges has increased as major infrastructure ages and is required to sustain loads that are significantly greater than those predicted during design.
Brown, CJ, Ogundipe, O, Roberts, GW
core   +1 more source