Results 211 to 220 of about 34,912 (272)

Enhancing Clinical Trial Selection for Cancer Patients Using Large Language Models. [PDF]

Cancer Inform
Gandy L, Tilli F.
europepmc   +1 more source

”Not always the magic bullet”—Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome

Epilepsia Open, EarlyView.
Abstract Objective Ketogenic dietary therapies (KDTs) are the treatment of choice for Glut1 Deficiency Syndrome (Glut1DS), providing dietary ketones as an alternative fuel to the brain and effectively controlling seizures. Recent evidence indicates insufficient seizure control in Glut1DS patients despite adequate KDT and ketosis.
Joerg Klepper, Eva Runkel, Lucia Kiesel
wiley   +1 more source

Bacterial Biohybrids With Dual Magnet and Hypoxia Tropism for Ferroptosis Activation in Deep Tumor Regions

Exploration, EarlyView.
This study introduces a bacterial biohybrid (Ec@ZFOY) designed to target deep tumor regions using a combination of magnetic and hypoxia‐driven mechanisms for enhanced therapeutic delivery. By incorporating hypoxia‐targeted Escherichia coli and magnetic nanoparticles loaded with a HIF‐1α inhibitor, the biohybrid activates ferroptosis through reactive ...
Sijie Shao, Huilan Zhuang, Tingjie Bai, Xuemei Zeng, Angelo Homayoun All, Shuangqian Yan   +5 more
wiley   +1 more source

Integrating GPT-4o Into Data Mining in Neurosurgery: Feasibility and Proof-of-Concept Study. [PDF]

JMIR Form Res
Almeida Sales AH, Beck J, Grauvogel J.
europepmc   +1 more source

EnzRetro: Enzymatic Retrosynthetic Planning With Site‐Specific Reaction Edits Based on Sequence Generative Architecture

Exploration, EarlyView.
EnzRetro bridges retrosynthesis planning and enzymatic engineering through site‐specific reaction edits. This end‐to‐end framework integrates pathway synthesis and enzyme identification into a unified process, achieving superior accuracy and enabling the efficient reconstruction of diverse biosynthetic pathways.
Yahui Cao, Haoshu Chen, Tao Zhang, Xin Zhao, Bingzhi Li, Xiangrui Zheng   +5 more
wiley   +1 more source

Preclinical HistoBench: A Pilot Benchmark Dataset for Evaluating Large Language Models on Preclinical Histopathological Classification. [PDF]

Biology (Basel)
Kader A, Ranner-Hafferl MHH, Reuter F, Fichtner ML, Makowski MR, Bressem KK, Adams LC.   +6 more
europepmc   +1 more source

Forecasting Count Data With Varying Dispersion: A Latent‐Variable Approach

Journal of Forecasting, EarlyView.
ABSTRACT Count data, such as product sales and disease case counts, are common in business forecasting and many areas of science. Although the Poisson distribution is the best known model for such data, its use is severely limited by its assumption that the dispersion is a fixed function of the mean, which rarely holds in real‐world scenarios.
Easton Huch, Candace Berrett, Mason Ferlic, Kimberly F. Sellers   +3 more
wiley   +1 more source

Disclaimers and Referral Patterns for Medical Advice Across Urgency Levels: Large Language Model Evaluation Study.

J Med Internet Res
Reis F, Agha-Mir-Salim L, Hickstein R, Reis M, Piper SK, Balzer F, Boie SD.   +6 more
europepmc   +1 more source

A Survey on Medical Competence Evaluation Benchmarks for Large Language Models. [PDF]

Health Care Sci
Wang Q, Zou H, Zhang H, Huang Y, Tian J, Cheng W.   +5 more
europepmc   +1 more source

Predicting and Preventing Turnover in Industry 4.0: Understanding the Impact of Artificial Intelligence Adoption on Employee Turnover

Human Resource Development Quarterly, EarlyView.
ABSTRACT With the increasing adoption of Artificial Intelligence (AI) in the workplace, employees' career paths have become more diverse and less predictable in the era of Industry 4.0. As technological transformations accelerate, employee turnover patterns are also changing, as reflected in the growing prevalence of occupational transitions and large ...
Young‐Kook Moon, Tanya Mitropoulos
wiley   +1 more source