Results 141 to 150 of about 98,573 (298)

Using Openai’s Chat GPT in Accounting: Pros, Cons Ethical Issues and Evaluating Its Role in Supporting Double-Entry Bookkeeping [PDF]

open access: yes
: Purpose. This study researches the distinctive integration of OpenAI’s Chat GPT within the domain of accounting, placing a particular emphasis on evolving ethical considerations.
Spasic, Dejan   +3 more
core  

Hepatocyte CBX2 Safeguards Hepatic Lipid Homeostasis by Elevating Ca2+‐CaMKK2‐AMPK Signaling to Counter MASLD

open access: yesAdvanced Science, EarlyView.
In hepatocytes, CBX2 promotes H3K4me3 enrichment at the Orai1 promoter to enhance Orai1 transcriptional activation, thereby increasing intracellular Ca2+ levels. The elevated Ca2+ activates the CaMKK2‐AMPK signaling cascade, resulting in ACC phosphorylation and downstream metabolic regulation. This cascade suppresses de novo lipogenesis (Fasn, Acc, Scd‐
Xiang Wei   +18 more
wiley   +1 more source

An AI‐Driven Framework for Directed Self‐Assembly Toward Design‐Technology Co‐Optimization

open access: yesAdvanced Science, EarlyView.
An artificial intelligence (AI)‐driven closed‐loop framework integrates experiment, three‐dimensional physics‐based simulation, and template design for directed self‐assembly (DSA). Guided by experimental data, AI‐assisted calibration accelerates model optimization, supports morphology prediction, and identifies template windows.
Caiwei Shang   +9 more
wiley   +1 more source

Assessing GPT-4o and GPT-4 in answering and explaining ophthalmology examination questions from Taiwan’s medical licensing test

open access: yesTaiwan Journal of Ophthalmology
PURPOSE: This study aims to evaluate and compare the performance of generative pretrained transformer (GPT)-4o and GPT-4 in answering Taiwan’s National Medical Licensing Examination (NMLE) ophthalmology questions from 2014 to 2023, focusing on both ...
Chen-Wei Lin   +4 more
doaj   +1 more source

Revista Gestión de las Personas y Tecnología - Versión Completa PDF

open access: yes
https://www.revistagpt.usach.cl/es/revista-gpt-edici%C3%B3n-n%C2%B0-09-noviembre ...
Revista GPT, Editorial
core   +1 more source

The VCPIP1‐UBE3A Deubiquitination‐Ubiquitination Cascade Contributes to Castration‐Resistant Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
VCIPIP1 emerges as a molecular link between protein stability and prostate cancer progression. By deubiquitinating and stabilizing UBE3A, VCIPIP1 promotes p53 degradation and progression to castration‐resistant prostate cancer. Elevated VCIPIP1 expression is associated with shorter castration‐resistant prostate cancer–free survival, highlighting the ...
Fei Lin   +9 more
wiley   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang   +7 more
wiley   +1 more source

Performance of ChatGPT and Bard on the medical licensing examinations varies across different cultures: a comparison study

open access: yesBMC Medical Education
Background This study aimed to evaluate the performance of GPT-3.5, GPT-4, GPT-4o and Google Bard on the United States Medical Licensing Examination (USMLE), the Professional and Linguistic Assessments Board (PLAB), the Hong Kong Medical Licensing ...
Yikai Chen   +8 more
doaj   +1 more source

Surface‐Selective Pt Enrichment for Stabilizing Ultrathin 2D PtCu Nanosheets Toward Durable Oxygen Reduction

open access: yesAdvanced Science, EarlyView.
Ultrathin 2D alloy nanosheet catalysts could offer exceptional catalytic activity but suffer from severe structural instability. Here, a surface‐selective Pt enrichment strategy via galvanic replacement effectively stabilizes PtCu Nanosheets while preserving their ∼ 1 nm thickness and (111) facets.
HyunWoo J. Yang   +7 more
wiley   +1 more source

Adaptive Cellular Responsiveness to Electrical Stimulation at the Skin‐Electrode Interface

open access: yesAdvanced Science, EarlyView.
This study presents an adaptive bioelectronic response in which sustained electrical stimulation (ES) upregulates voltage‐gated calcium channels (VGCCs) and enhances cellular sensitivity to subsequent ES at the skin‐device interface. VGCC‐associated adaptive sensitization promotes regenerative wound‐healing responses in vivo, including accelerated ...
Yeon Jae Chang   +11 more
wiley   +1 more source

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