Results 211 to 220 of about 98,573 (298)

Animal models for investigating post‐stroke cognitive impairment: A neurovascular trafficking perspective

Animal Models and Experimental Medicine, EarlyView.
Animal models enable mechanistic testing of how ischemic injury disrupts neurovascular trafficking and drives cognitive vulnerability after stroke. Complementary models capture distinct vascular, cellular, white matter, and cognitive features of PSCI.
Pratchaya Kaewkaen
wiley   +1 more source

Accelerated Epigenetic Aging in Frontotemporal Dementia Highlights Smoking, Inflammation, and Metabolic Signals

Annals of Neurology, EarlyView.
Objective Epigenetic clocks are biomarkers of biological aging influenced by lifestyle and systemic factors. Accelerated epigenetic aging has been associated with neurodegeneration, but its relevance in frontotemporal dementia is unclear. We investigated biological aging in frontotemporal dementia using the GrimAge2 epigenetic clock, a DNA methylation ...
Daphne Nijland, Sven J. van der Lee, Eska Marye de Haan, Naren Ramesh, Sterre C.M. de Boer, Everard G.B. Vijverberg, Henne Holstege, Yolande A.L. Pijnenburg, Roel A. Ophoff, Lianne M. Reus   +9 more
wiley   +1 more source

Harnessing large language models for reliable automatic Charlson Comorbidity Index scoring: a validation study. [PDF]

JAMIA Open
Borcard LM, Calek AK, Rebsamen M, Herzog B, Caprara S, Farshad M, Bauer DE.   +6 more
europepmc   +1 more source

Prediction of First and Recurrent Falls in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective To develop and externally validate prediction models for next‐year falls in Parkinson's disease (PD), and to evaluate the incremental value of imaging and fluid biomarkers. Methods We developed models in Parkinson's Progression Markers Initiative (PPMI) to predict next‐year falls with external validation in University of Pennsylvania (UPenn ...
Joaquin A. Vizcarra, Kat Hefter, Michael Tran Duong, Ashkan Ertefaie, Umberto Tachinardi, Christopher A. Olm, Hamsanandini Radhakrishnan, Corey T. McMillan, David Irwin, Daniel Weintraub, Brian Litt, Dani S. Bassett, Andrew Siderowf, The Parkinson's Progression Markers Initiative   +13 more
wiley   +1 more source

Evaluating large language models for lay summaries of radiology reports using tailored prompting strategies and mixed-method assessment. [PDF]

PLOS Digit Health
Tasneem N, van der Pol CB, Zahoor A, Juggath N, McGowan K, Lokker C, Saha A.   +6 more
europepmc   +1 more source

Systematic Scoring Differences in Large Language Model-Based Clinical Benchmarking Reveal Evaluator-Dependent Divergence: Controlled Evaluation Study. [PDF]

JMIR AI
Dinc R, Ardic N.
europepmc   +1 more source

GPT intern [PDF]

Zeitschrift für Phytotherapie, 2017
openaire   +1 more source

Germa‐Michael Addition: Substratbreite, Mechanismus und Zugang zu Biokompatiblen Wasserlöslichen Typ‐I‐Photoinitiatoren

Angewandte Chemie, EarlyView.
Wir beschreiben die erste Germa‐Michael‐Addition zur Synthese eines wasserlöslichen Germanium‐Photoinitiators mit hoher Initiierungseffizienz, Stabilität und geringer Zytotoxizität. Ein NHS‐Ester eröffnet Möglichkeiten zur Biokonjugation, während doppelte Additionen das Funktionalisierungsspektrum erweitern.
Matthias Paris, David Vorcnik, Renata Raptova, Mathias Wiech, Nils Ansmann, Zizheng Zhang, Ana Torvisco, Roland C. Fischer, Christine Bandl, Julia Fuchs, Dagmar Brislinger, Lutz Greb, Georg Gescheidt, Michael Haas   +13 more
wiley   +1 more source

Performance of Cloud-Hosted Large Vision-Language Models on the Japanese National Examination for Clinical Laboratory Technicians: Comparative Benchmarking Study. [PDF]

JMIR Med Educ
Murakami K, Matsuzawa R, Tahara-Arai Y, Ozaki H.   +3 more
europepmc   +1 more source