Results 41 to 50 of about 137,842 (266)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Educational Technology & SocietyIn massive open online course (MOOC) environments, computer-based analysis of course reviews enables instructors and course designers to develop intervention strategies and improve instruction to support learners’ learning.
Xieling Chen, Haoran Xie, Di Zou, Lingling Xu, Fu Lee Wang
doaj +1 more source
Humans are still better than ChatGPT: Case of the IEEEXtreme competition
Heliyon, 2023 Since the release of ChatGPT, numerous studies have highlighted the remarkable performance of ChatGPT, which often rivals or even surpasses human capabilities in various tasks and domains.
Anis Koubaa +5 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Proceedings of the International Conference on Applied Innovations in ITModern global crises have significantly impacted the agribusiness sector, particularly poultry farming, which has experienced issues with logistics, labor shortages, and disruptions in the supply of feed and veterinary drugs.
Svitlana Antoshchuk +2 more
doaj +1 more source
Numerical Computation of approximate Generalized Polarization Tensors
, 2011 In this paper we describe a method to compute Generalized Polarization Tensors. These tensors are the coefficients appearing in the multipolar expansion of the steady state voltage perturbation caused by an inhomogeneity of constant conductivity.
Capdeboscq, Yves +2 more
core +3 more sources
Revista Mexicana de Ciencias Penales, 2023 El nacimiento de ChatGPT ha significado un punto de partida para la reflexión del lugar que la inteligencia artificial debe jugar en nuestra vida cotidiana, dejando de pertenecer exclusivamente al área de la ciencia ficción. Entre sus usos se debe considerar también su utilidad como herramienta para la comisión de delitos, dada su capacidad para ...
openaire +1 more source
DroidBot-GPT: GPT-powered UI Automation for Android
, 2023 8 pages, 5 ...
Wen, Hao +3 more
openaire +2 more sources
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
, 2009 We develop a systematic approach to construct novel completely solvable rational potentials. Second-order supersymmetric quantum mechanics dictates the latter to be isospectral to some well-studied quantum systems.
A. A. Andrianov +34 more
core +1 more source