Functional redundancy between RAP1 isoforms in murine platelet production and function [PDF]
RAP GTPases, important regulators of cellular adhesion, are abundant signaling molecules in the platelet/megakaryocytic lineage. However, mice lacking the predominant isoform, RAP1B, display a partial platelet integrin activation defect and have a ...
Becker +91 more
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A Novel Viper Venom Metalloproteinase, Alborhagin, Is an Agonist at the Platelet Collagen Receptor GPVI [PDF]
Robert K. Andrews +8 more
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Tangeretin regulates platelet function through inhibition of phosphoinositide 3-Kinase and cyclic nucleotide signaling [PDF]
OBJECTIVE: Dietary flavonoids have long been appreciated in reducing cardiovascular disease risk factors, but their mechanisms of action are complex in nature.
Ali, Marfoua S. +6 more
core +1 more source
Distinct roles of GPVI and integrin α2β1 in platelet shape change and aggregation induced by different collagens [PDF]
Gavin E. Jarvis +3 more
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The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function [PDF]
Background: Thiol isomerases are a family of endoplasmic reticulum enzymes which orchestrate redox-based modifications of protein disulphide bonds. Previous studies have identified important roles for the thiol isomerases PDI and ERp5 in the regulation ...
Bicknell, Andrew B. +5 more
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Analysis of the Interaction of Platelet Collagen Receptor Glycoprotein VI (GPVI) with Collagen [PDF]
Yoshiki Miura +3 more
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Ginsenoside Rg5 inhibits platelet aggregation by regulating GPVI signaling pathways and ferric chloride-induced thrombosis [PDF]
Akram A +10 more
europepmc +2 more sources
Collagen platelet receptor polymorphisms integrin α2β1 C807T and GPVI Q317L and risk of ischemic stroke [PDF]
Vanessa Cole +7 more
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Das Hühner CLEC-2 Homolog [PDF]
Das Hühner CLEC-2 Homolog: Ein Thrombozytenrezeptor mit aktivierender Funktion Der Natürliche Killer Gen Komplex (NKC) des Huhnes ist auf dem Chromosom 1 lokalisiert und weist zwei C-typ Lektine auf, von denen das eine als Homolog zu CD69 und das andere
Neulen, Marie-Luise
core
Differential regulation of actin stress fiber assembly and proplatelet formation by α2β1 integrin and GPVI in human megakaryocytes [PDF]
Siham Sabri +6 more
openalex +1 more source

