Results 171 to 180 of about 594 (208)

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

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Status of the GRACE Follow-On Mission

2014
The Gravity Recovery and Climate Mission (GRACE) has been so far the only satellite mission capable of monitoring mass variations in the Earth system and has made many breakthroughs in the understanding of Earth system dynamics. The mission has been operating for over 10 years at the time of this paper.
Flechtner, F., Morton, P., Watkins, M., Webb, F.   +3 more
openaire   +5 more sources

International challenges of GRACE Follow-On

2017 IEEE Aerospace Conference, 2017
The Gravity Recovery and Climate Experiment-Follow-On (GRACE-FO) Mission is a NASA directed mission to continue the goals of the original GRACE mission and provide continuity for the GRACE data set. The GRACE-FO mission is the result of an international cooperation to develop a concept and approach that minimizes cost and risk and maximizes the ...
Sammy Kayali, Phillip Morton, Michael Gross   +2 more
openaire   +1 more source

V04 Level-1 data processing status for GRACE and GRACE Follow-On

2020
<p>On May 22, 2020, the Gravity Recovery and Climate Experiment Follow-On (GRACE-FO), will celebrate two years of successful in-orbit operation. The primary goal of this satellite mission is to provide information about time variations of the Earth’s gravity field. This is possible due to precise orbit determination
Tamara Bandikova, Hui Ying Wen, Meegyeong Paik, William Bertiger, Mark Miller, Nate Harvey, Christopher McCullough, Christopher Finch, Sung Byun, Da Kuang, Felix Landerer, Carmen Boening   +11 more
openaire   +1 more source

Overview of the GRACE Follow-on Mission

Light, Energy and the Environment, 2014
The GRACE Follow-on mission will map Earth’s gravity to monitor melting of polar ice and changes in continental ground water. We present GRACE Follow-on’s new laser ranging instrument developed by US, German and Australian scientists.
openaire   +1 more source

Combining global hlSST and SLR to bridge the gap between GRACE and GRACE-Follow

2023
GRACE and GRACE-Follow On time series suffer from a data gap of about one year and there is the need for an intermediate technique that will bridge the gap between the two missions. The combination of high-low satellite-to-satellite tracking (hlSST) of low-Earth orbiting satellites by GNSS in combination with SLR is the most promising candidate ...
Weigelt, M., Jäggi, A., Meyer, U., Arnold, D., Mayer-Gürr, T., Öhlinger, F., Sośnica, K., Ebadi, S., Steffen, H.   +8 more
openaire   +2 more sources

The glacier changes in the Alps from the GRACE and GRACE Follow-On Missions

In this work, the time-variable gravity field data from the Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow-On (GRACE-FO) covering the period from April 2002 to September 2023 is used to quantify glacier mass changes in the Alps.
Shuxian Liu, Roland Pail
openaire   +1 more source

Following the Grace: A Baltic Dialogue

2015
The admiration of Alvar Aalto for the architecture of Erik Gunnar Asplund is well known and clearly expressed by his own writings, as well as the impact of the Stockholm Exhibition in his architectural experimentation. Likewise, the influence of the Mediterranean travels for the architecture of Alvar Aalto has been deep analyzed by many scholars.
TORRICELLI, CARLOTTA, Ursula, Koren
openaire   +2 more sources

Current Status Of The GRACE Follow-On Mission

2017
As of the time of this abstract submission, the GRACE Follow-On satellites have been constructed and transferredto Ottobrunn near Munich for several months of operational testing in the IABG test centre. The Russian/UkraineDnepr launcher had to be exchanged and a corresponding new contract has been signed by GFZ and IridiumSatellite LLC.
Flechtner, F., Webb, F., Watkins, M., Landerer, F., Dahle, C. ; https://orcid.org/0000-0002-4733-9242, Bettadpur, S.   +5 more
openaire   +1 more source