Results 51 to 60 of about 68,008,188 (287)

COST-G: towards a new GRACE and GRACE-FO combination

open access: yes, 2022
The combination service for time-variable gravity fields (COST-G) provides the full time-series of monthly GRACE gravity fields: COST-G GRACE RL01, combined in reprocessing mode, and a steadily growing time-series of monthly GRACE-FO gravity fields: COST-
Güntner, Andreas   +15 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Assessment of GRACE/GRACE Follow-On Estimates of Global Mean Ocean Mass Change

open access: yes, 2021
Abstract Global mean sea level has increased ~3.5 mm/yr over several decades due to increases in ocean mass and changes in sea water density. Ocean mass, accounting for about two-thirds of the increase, can be directly measured by the Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow-On (GFO) satellites. An independent measure is
Jae-Seung Kim   +3 more
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Co-Seismic and Post-Seismic Temporal and Spatial Gravity Changes of the 2010 Mw 8.8 Maule Chile Earthquake Observed by GRACE and GRACE Follow-on

open access: yesRemote Sensing, 2020
The Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow-on (GRACE-FO) satellites are important for studying regional gravitational field changes caused by strong earthquakes.
Wei Qu   +5 more
doaj   +1 more source

Comparison of GRACE and TIMI risk scores in the prediction of in-hospital and long-term outcomes among East Asian non-ST-elevation myocardial infarction patients

open access: yesBMC Cardiovascular Disorders, 2022
Background Risk stratification in non-ST segment elevation myocardial infarction (NSTEMI) determines the intervention time. Limited study compared two risk scores, the Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary ...
Lu Yanqiao   +4 more
doaj   +1 more source

Advertisements of follow-on formula and their perception by pregnant women and mothers in Italy

open access: yes, 2015
Objective To assess how follow-on formula milks for infants aged 6–12 months are presented to and understood by mothers. Design A quantitative and qualitative cross-sectional study including (1) an analysis of advertisements in three magazines for ...
Mutti, Valentina   +6 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Assimilation of GRACE Follow‐On Inter‐Satellite Laser Ranging Measurements Into Land Surface Models

open access: yesWater Resources Research, 2023
The monthly mean level‐2 (L2) time‐variable gravity as well as level‐3 (L3) Mass Concentration blocks (mascons) data from Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow‐On (GRACE‐FO) missions are frequently used for improving land ...
Mehdi Khaki   +4 more
doaj   +1 more source

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