Results 51 to 60 of about 40,128 (251)

Assessment of GRACE/GRACE Follow-On Estimates of Global Mean Ocean Mass Change

, 2021
Abstract Global mean sea level has increased ~3.5 mm/yr over several decades due to increases in ocean mass and changes in sea water density. Ocean mass, accounting for about two-thirds of the increase, can be directly measured by the Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow-On (GFO) satellites. An independent measure is
Jae-Seung Kim, Ki-Weon Seo, Jianli Chen, Clark Wilson   +3 more
openaire   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Progress in satellite gravity recovery from implemented CHAMP, GRACE and GOCE and future GRACE Follow-On missions

Geodesy and Geodynamics, 2015
Firstly, the Earth's gravitational field from the past Challenging Minisatellite Payload (CHAMP) mission is determined using the energy conservation principle, the combined error model of the cumulative geoid height influenced by three instrument errors ...
Wei Zheng, Houze Xu
doaj   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

High-Resolution Mass Trends of the Antarctic Ice Sheet through a Spectral Combination of Satellite Gravimetry and Radar Altimetry Observations

Remote Sensing, 2019
Time-variable gravity measurements from the Gravity Recovery and Climate Experiment (GRACE) and GRACE-Follow On (GRACE-FO) missions and satellite altimetry measurements from CryoSat-2 enable independent mass balance estimates of the Earth’s ...
Ingo Sasgen, Hannes Konrad, Veit Helm, Klaus Grosfeld   +3 more
doaj   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

A Probabilistic Approach to Characterizing Drought Using Satellite Gravimetry

Water Resources Research
In the recent past, the Gravity Recovery and Climate Experiment (GRACE) satellite mission and its successor GRACE Follow‐On (GRACE‐FO), have become invaluable tools for characterizing drought through measurements of Total Water Storage Anomaly (TWSA ...
Peyman Saemian, Mohammad J. Tourian, Omid Elmi, Nico Sneeuw, Amir AghaKouchak   +4 more
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Evaluation of GRACE/GRACE Follow-On Time-Variable Gravity Field Models for Earthquake Detection above Mw8.0s in Spectral Domain

Remote Sensing, 2021
This study compares the Gravity Recovery And Climate Experiment (GRACE)/GRACE Follow-On (GFO) errors with the coseismic gravity variations generated by earthquakes above Mw8.0s that occurred during April 2002~June 2017 and evaluates the influence of ...
Ming Xu, Xiaoyun Wan, Runjing Chen, Yunlong Wu, Wenbing Wang   +4 more
doaj   +1 more source