Results 81 to 90 of about 408 (250)

On $k$-Super Graceful Labeling of Graphs

open access: yes, 2018
Let $G=(V(G),E(G))$ be a simple, finite and undirected graph of order $p$ and size $q$. For $k\ge 1$, a bijection $f: V(G)\cup E(G) \to \{k, k+1, k+2, \ldots, k+p+q-1\}$ such that $f(uv)= |f(u) - f(v)|$ for every edge $uv\in E(G)$ is said to be a $k$-super graceful labeling of $G$.
Lau, Gee-Choon   +2 more
openaire   +3 more sources

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng   +7 more
wiley   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

open access: yesAdvanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao   +13 more
wiley   +1 more source

Edge-Graceful Labelings of Connected Graphs

open access: yesElectronic Notes in Discrete Mathematics, 2016
Abstract Let G be a connected edge-graceful ( p , q ) -graph with q = k p + r , where k is an integer and 0 ≤ r p . In this paper, we prove that every edge-graceful labeling f of G induces [ ( k + 1 ) ! ] r [ k ! ] p − r number of edge-graceful labelings of G.
K. Kayathri, R. Amutha
openaire   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

open access: yesAdvanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen   +15 more
wiley   +1 more source

Photo‐Triggered, Fast, and Fluorogenic Thiophene‐Based Cycloalkynes for the Bioorthogonal Fluorescent Labeling of 1,3‐Dipole‐Tagged Molecules in No‐Wash Conditions

open access: yesAngewandte Chemie, EarlyView.
Thiophene is king! The fusion of thiophene rings to cycloalkynes super‐charged their copper‐free click chemistry applications, by (1) enhancing the alkyne reactivity (fastest cyclooctyne to date) and (2) rendering the alkyne fluorogenic (with fluorescence enhancement up to 150‐fold upon reaction), making these bioorthogonal reagents ideal for tracking ...
Jurgen Schulz   +7 more
wiley   +2 more sources

On graceful labelings of trees

open access: yes, 2018
We prove via a composition lemma, the Kotzig-Ringel-Rosa conjecture, better known as the Graceful Labeling Conjecture. We also prove via a stronger version of the composition lemma a stronger form of the Graceful Labeling Conjecture.
openaire   +2 more sources

Nano‐Confined Radical Anion as An NIR‐II Photothermal Immunogenic Amplifier for In Situ Cancer Vaccination

open access: yesAdvanced Science, EarlyView.
A nano‐confined radical anion acts as a photothermal immunogenic amplifier. Kinetically stabilized nanoparticles couple high near‐infrared‐II (NIR‐II) photothermal efficacy with glutathione (GSH) depletion to boost reactive oxygen species (ROS) and immunogenic cell death (ICD).
Mengxin Mu   +9 more
wiley   +1 more source

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