Results 51 to 60 of about 337 (211)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Forecasting Retail Sales for Furniture and Furnishing Items through the Employment of Multiple Linear Regression and Holt–Winters Models

Systems
Global economic growth, marked by rising GDP and population, has spurred demand for essential goods including furniture. This study presents a comprehensive demand forecasting analysis for retail furniture sales in the U.S.
Melike Nur İnce, Çağatay Taşdemir
doaj   +1 more source

Pugge kritisk tenkning? Om religionskritikk i lærebøker for KRLE

Prismet, 2018
Artikkelen undersøker kapittelet om religionskritikk i to læreverk for KRLE. Analysen gjelder kritikkens innhold. I forlengelsen av dette drøfter artikkelen på hvilken måte og i hvilken grad læreboktekstene er transparente for elevene slik at de blir ...
Kristin Hatlebrekke
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Investigating the influence of reflective materials on indoor thermal environment and solar reflectance in buildings

Case Studies in Thermal Engineering
This in-depth study explores the intricate dynamics of reflective materials, emphasizing their impact on the indoor thermal environment and urban heat island (UHI) mitigation.
Jihui Yuan, Yasuhiro Shimazaki, Masaki Tajima, Shaoyu Sheng, Zhichao Jiao, Marko Bizjak   +5 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Impact of Band Nonparabolicity on Threshold Voltage of Nanoscale SOI MOSFET

Active and Passive Electronic Components, 2016
This paper reconsiders the mathematical formulation of the conventional nonparabolic band model and proposes a model of the effective mass of conduction band electrons including the nonparabolicity of the conduction band.
Yasuhisa Omura
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Shading effects on building energy performance: A multi-city analysis

Results in Engineering
This study presents a simplified methodology to evaluate the effects of surrounding shading elements—such as nearby buildings and trees—on building thermal loads, with a focus on passive cooling.
Xiong Xiao, Jihui Yuan, Zhichao Jiao, Shaoyu Sheng, Jiale Chai, Xiangfei Kong, Craig Farnham, Kazuo Emura   +7 more
doaj   +1 more source