Results 71 to 80 of about 8,504,958 (293)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Transitioning to Grad School

open access: yes, 2013
I love this time of year, as the weather cools I find the entire campus pregnant with anticipation for the new students to arrive. This year is especially exciting for me as we welcome the first class of MA students that I had influence over their admission.
openaire   +2 more sources

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

Educational robotics as a pedagogical resource for K-12 students with learning difficulties

open access: yesScientific Reports
Learning difficulties in children can have a variety of causes, often interconnected. Factors such as emotional problems (anxiety, stress), communication difficulties, inadequate teaching methodologies, health problems, lack of family support, and even ...
Maria da Guia Torres da Silva   +4 more
doaj   +1 more source

Impact of Band Nonparabolicity on Threshold Voltage of Nanoscale SOI MOSFET

open access: yesActive and Passive Electronic Components, 2016
This paper reconsiders the mathematical formulation of the conventional nonparabolic band model and proposes a model of the effective mass of conduction band electrons including the nonparabolicity of the conduction band.
Yasuhisa Omura
doaj   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

open access: yesAging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara   +3 more
wiley   +1 more source

Drivers of urban heat island in Osaka: Morphology versus green-blue infrastructure

open access: yesNext Sustainability
This study examines ward-level relationships between satellite-derived land surface temperature (LST), urban morphology, and land-cover indices in Osaka Prefecture, Japan.
Xiong Xiao, Craig Farnham, Jihui Yuan
doaj   +1 more source

Wikipedia Goes to Grad School [PDF]

open access: yesScience, 2010
Education Very few graduate-level science curricula include training in communicating advanced concepts to a general audience. Moy et al. report a class project that addressed this by having chemistry students edit an entry in [Wikipedia.org][1] collaboratively.
openaire   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

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