Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Ser joven en el Perú : educación y trabajo [PDF]
A pesar del crecimiento sostenido que ha experimentado el Perú durante la última década, aún existen indicadores de desarrollo que requieren mejoras importantes. Entre los más urgentes, los del mercado laboral.
Franco, Ana Paula +2 more
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STAT3 as a potential molecular target to sensitize colorectal cancer cells to chemoradiotherapy [PDF]
Grade, Marian
core +2 more sources
Grade Prediction Is Not Grading
Jan Georg Schneider, Katharina A. Zweig
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Does Taking One Step Back Get You Two Steps Forward? Grade Retention and School Performance in Rural China [PDF]
: Despite the rise in grade retention in China recently, little work has been done to understand the impact of grade retention on the educational performance of students in China.
Rozelle, Scott +2 more
core +1 more source
Comprendiendo el embarazo, la convivencia y el matrimonio en la adolescencia : el caso del Perú [PDF]
En las encuestas de Niños del Milenio y estadísticas nacionales, 1 de cada 5 mujeres a los 19 años tenía al menos un hijo. Se propone reforzar políticas públicas para postergar el embarazo adolescente: concluir la secundaria, mejorar la educación sexual ...
Fávara, Marta +3 more
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Political Economy of Exchange Rate Policies in Latin America and the Caribbean: The Case of Peru [PDF]
The main objective of this document is to identify structural long-term factors that can help to understand the exchange rate policy in Peru during the last fifty years.
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