Results 61 to 70 of about 987,516 (263)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Clinical Significance of Tumor Grade in Triple-Negative Breast Cancer: A Retrospective Cohort Analysis

open access: yesBiomedicines
Triple-negative breast cancer (TNBC) is a heterogeneous cancer that lacks estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor 2 (HER2) proteins.
Neya Ramanan   +14 more
doaj   +1 more source

Graded Signatures

open access: yes, 2015
Motivated by the application of anonymous petitions, we formalize a new primitive called "graded signatures", which enables a user to consolidate a set of signatures on a message m originating from l different signers that are members of a PKI. We call the value $$l \in \mathbb {N}$$l∈N, the grade of the consolidated signature.
Aggelos Kiayias   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A MODIFIED CASE STUDY EXAMINING THE EFFECTS OF SPECIFIC SCHOOL GRADE-LEVEL ORGANIZATIONAL MODELS ON NINTH-GRADE LEARNERS [PDF]

open access: yes, 2014
This doctoral dissertation represents a qualitative study employing a modified case study research design that is intended to assess the perspectives of school practitioners (i.e., principals, guidance counselors, and teachers) who work with ninth ...
Frioni, Robert
core  

Critical appraisal of systematic reviews and meta-analyses

open access: yesIndian Journal of Anaesthesia
Systematic reviews and meta-analyses (SRMAs) are cornerstone methodologies in evidence-based medicine, synthesising vast research to provide comprehensive insights.
Kapil D. Soni
doaj   +1 more source

Sistemas de preparo e resistência à penetração e densidade de um Latossolo Vermelho eutrófico em cultivo intensivo e pousio [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2002
O manejo inadequado do solo causa a sua degradação e à queda no rendimento de muitas culturas. O objetivo deste trabalho foi avaliar alterações na resistência à penetração e na densidade do solo em razão de sistemas de preparo do solo, durante e após o ...
Renato de Mello Prado   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Types of glioma brain tumors and genetic alterations in signaling pathways in them [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2019
Types of glioma brain tumors and genetic alterations in signaling pathways in them Background & Objective: Glioma is a common type of primary brain tumor originating in the glial cells that surrounds and supports neurons in the brain.
narges ahani   +3 more
doaj  

CT-Based Radiomics Signature for the Preoperative Discrimination Between Head and Neck Squamous Cell Carcinoma Grades

open access: yesFrontiers in Oncology, 2019
Background: Radiomics has been widely used to non-invasively mine quantitative information from medical images and could potentially predict tumor phenotypes.
Wenli Wu   +4 more
doaj   +1 more source

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