Results 31 to 40 of about 5,548,099 (224)

Graded early warning for crude oil tanks based on TOPSIS

open access: yesYou-qi chuyun
Objective Given the rise in large-scale and centralized crude oil tanks, along with the physical and chemical properties of crude oil and the intricate nature of tank materials and components, these tanks present substantial risks.
Gang WU   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Graded Ideal Semiprima [PDF]

open access: yes, 2014
Pada skripsi ini dibahas mengenai graded ideal semiprima dari -graded ring komutatif dengan elemen identitas tak nol. Suatu -graded ring komutatif dengan elemen identitas tak nol didefinisikan sebagai direct sum subgrup-subgrup aditif sebanyak order grup
Anggraini, Rosalina
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

On the Hilbert depth of the Hilbert function of a finitely generated graded module

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
Let K be a field, A a standard graded K-algebra and M a finitely generated graded A-module. Inspired by our previous works, see [2] and [3], we study the invariant called Hilbert depth of hM, that is hdepth(hM)=max{d:∑j≤k(-1)k-j(d-jk-j)hM(j)≥0  for  all ...
Bălănescu Silviu, Cimpoeaş Mircea
doaj   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

open access: yesFEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti   +4 more
wiley   +1 more source

On graded prime and primary submodules

open access: yes, 2011
Let G be a multiplicative group. Let R be a G-graded commutative ring and M a G-graded R-module. Various properties of graded prime submodules and graded primary submodules of M are discussed.
TEKİR, ÜNSAL   +5 more
core   +2 more sources

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

open access: yesFEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

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