Results 61 to 70 of about 486,078 (247)
On the multiplicity of tangent cones of monomial curves
, 2018 Let $\Lambda$ be a numerical semigroup, $\mathcal{C}\subseteq \mathbb{A}^n$ the monomial curve singularity associated to $\Lambda$, and $\mathcal{T}$ its tangent cone.
Sammartano, Alessio
core +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
On the Hilbert depth of the Hilbert function of a finitely generated graded module
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria MatematicaLet K be a field, A a standard graded K-algebra and M a finitely generated graded A-module. Inspired by our previous works, see [2] and [3], we study the invariant called Hilbert depth of hM, that is hdepth(hM)=max{d:∑j≤k(-1)k-j(d-jk-j)hM(j)≥0 for all ...
Bălănescu Silviu, Cimpoeaş Mircea
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Betti numbers of powers of ideals
Le Matematiche, 2008 Let A=K[x1, ..... ,xn] be a standard graded polynomial ring over a field K, let M = (x_1, .... , x_n) be the graded maximal ideal and I a graded ideal of A.
Gioia Failla +2 more
doaj
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source
The Hilbert–Kunz Function in Graded Dimension Two [PDF]
, 2004 Let R denote a two-dimensional normal standard-graded K-domain over the algebraic closure K of a finite field of characteristic p, and let I ⊂ R denote a homogeneous R +-primary ideal.
Holger Brenner
semanticscholar +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source