Results 101 to 110 of about 21,796,219 (281)

9. Vorlesung (20.12.2018): Graded-Response-Modelle

open access: yes, 2018
Vorlesungsinhalte: Analyse der Gut-Schlecht-Skala des MDBF mit dem Partial-Credit-Model (Winmira); Graded-Response-Modelle mit Logit- und Probit-Linkfunktion; Analyse der Gut-Schlecht-Skala des MDBF mit Graded-Response-Modellen, mit Logit-
Multimediazentrum, Steyer, Rolf
core  

Analysis of functionally graded sandwich plates using a new first-order shear deformation theory [PDF]

open access: yes, 2014
In this paper, a new first-order shear deformation theory is presented for functionally graded sandwich plates composed of functionally graded face sheets and an isotropic homogeneous core. By making a further assumption to the existing first-order shear
Thai, Huu-Tai   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Bayesian Estimation of a Multi-Unidimensional Graded Response IRT Model

open access: yesBehaviormetrika, 2015
Unidimensional graded response models are useful when items are designed to measure a unified latent trait. They are limited in practical instances where the test structure is not readily available or items are not necessarily measuring the same underlying trait.
Kuo, Tzu-Chun, Sheng, Yanyan
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Factor Structure and Measurement Invariance Across Gender of the Eating Disorder Examination Questionnaire—Short Form in Italian Workers

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
Eating disorders (EDs) are complex conditions that can significantly affect health and productivity, yet their assessment in occupational settings remains underexplored.
Nicola Magnavita, Carlo Chiorri
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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