Results 71 to 80 of about 193,208 (246)
Robust estimation of the latent trait in graded response models
Behavior Research MethodsAbstract Aberrant responses (e.g., careless responses, miskeyed items, etc.) often contaminate psychological assessments and surveys. Previous robust estimators for dichotomous IRT models have produced more accurate latent trait estimates with data containing response disturbances. However, for widely used Likert-type items with three or more
Audrey Filonczuk, Ying Cheng
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Alexandria Engineering Journal, 2018 With the widespread application of composite structures in engineering, the static and dynamic analyses of these structures have become important in the past years.
Hadi Ghashochi-Bargh, Soheil Razavi
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
European Journal of Investigation in Health, Psychology and EducationEating disorders (EDs) are complex conditions that can significantly affect health and productivity, yet their assessment in occupational settings remains underexplored.
Nicola Magnavita, Carlo Chiorri
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Modeling graded response congruency effects in task switching
Acta Psychologica, 2014 Compound cue retrieval is a computational model of a mediated route for response selection in task-switching situations. In previous studies, the model has been shown to account for response congruency effects when switching between two tasks, where response congruency reflects the degree of match between relevant and irrelevant task responses ...
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Bayesian Estimation of a Multi-Unidimensional Graded Response IRT Model
Behaviormetrika, 2015 Unidimensional graded response models are useful when items are designed to measure a unified latent trait. They are limited in practical instances where the test structure is not readily available or items are not necessarily measuring the same underlying trait.
Kuo, Tzu-Chun, Sheng, Yanyan
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