Results 51 to 60 of about 903,684 (295)
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Consider a pseudo-$H$-space $E$ endowed with a separately continuous biadditive associative multiplication which induces a grading on $E$ with respect to an abelian group $G$. We call such a space a graded pseudo-$H$-ring and we show that it has the form $E = cl(U + \sum_j I_j)$ with $U$ a closed subspace of $E_1$ (the summand associated to the unit ...
Calderón Martín, Antonio Jesús +3 more
openaire +5 more sources
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
On graded P-compactly packed modules
Let G be a group with identity e. Let R be a G-graded commutative ring and M a graded R-module. In this paper, we introduce the concept of graded P-compactly packed modules and we give a number of results concerning such graded modules.
Al-Zoubi Khaldoun +2 more
doaj +1 more source
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
On the asymptotic behaviour of graded generalized local cohomology modules [PDF]
Let ${R=igoplus_{ngeq 0}R_n}$ be a graded Noetherian ring withlocal base ring $R_0$ and let ${R_{+}=igoplus_{ngeq 1}R_n}$.Let $M$ and $N$ be finitely generated graded $R$-modules. In thispaper, we prove some results on the asymptotic behaviour of the$n$-
F. Dehghani-Zadeh
doaj
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Sign gradations on group-ring extensions of graded rings
For a (group)G-graded ring R and any submonoid H of the center Z(G) containing the identity element e of G we define a G-gradation on the semigroup ring R[H] such that R[H]e ≅ R(H) where R(H) = ⊕h∈HRh⊆R, and then we give some applications of the new ...
Li, Hui-Shi +3 more
core +1 more source
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source

