Results 71 to 80 of about 30,010 (264)
Journal of Pure and Applied Algebra, 2012 24 pages with a few corrections and minor ...
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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On graded \(J\)-ideals over graded rings
, 2023 Summary: The goal of this article is to present the graded \(J\)-ideals of \(G\)-graded rings which are extensions of \(J\)-ideals of commutative rings. A graded ideal \(P\) of a \(G\)-graded ring \(R\) is a graded \(J\)-ideal if whenever \(x,y\in h(R)\), if \(xy\in P\) and \(x\not\in J(R)\), then \(y\in P\), where \(h(R)\) and \(J(R)\) denote the set ...
Al-Shorman, Tamem +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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Journal of Algebra, 1984 A ring R is said to be a G\(E_ 2\)-ring if \(GL_ 2(R)\), the group of 2\(\times 2\) invertible matrices over R, is generated by elementary and diagonal matrices. The author obtains some necessary conditions for a graded domain to be a \(GE_ 2\)-ring. This gives rise to a number of interesting consequences. Amongst other things it is proved, for example,
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
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On Lie rings of torsion groups
Bulletin of Mathematical Sciences, 2016 We prove that the Lie ring associated to the lower central series of a finitely generated residually-p torsion group is graded nil.
Consuelo Martínez, Efim Zelmanov
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