Results 91 to 100 of about 848,438 (282)
Semigroup gradings on associative rings
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Yuri A. Bahturin, Mikhail V. Zaicev
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Some Results on Graded Generalized Local Cohomology Modules
. Let R = ⊕n>0Rn be a graded Noetherian ring with local base ring R0 and let R+ = ⊕n>1Rn. Let M and N be finitely generated graded R-modules. In this paper we extend some of the known results about ordinary local cohomology modules Hi R+ (M) to ...
F. Dehghani-Zadeh, H. Zakeri
doaj
On graded Jgr-2-absorbing primary submodule
This paper introduces the concept of graded Jgr-2-absorbing primary submodules, a new intermediate structure in graded module theory. Motivated by the need to extend and unify classical notions such as graded prime and graded primary submodules, the ...
Shatha Alghueiri, Khaldoun Al-Zoubi
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Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Conditions ($S_q$) and ($G_q$) on graded rings
Let be a commutative noetherian gradedring. We study Serre's condition and Ischebeck-Auslander's conditionin the graduate case. Let be an integer, we characterize the -torsion freeness of graded modules on a -ring.
La Barbiera, M
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Splines on Cayley graphs of the symmetric group
A spline is an assignment of polynomials to the vertices of a graph whose edges are labeled by ideals, where the difference of two polynomials labeling adjacent vertices must belong to the corresponding ideal. The set of splines forms a ring. We consider
Nathan R. T. Lesnevich
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